Enterobacteriaceae - Salmonella

Question 1

What is an important specie of Salmonella

Answer 1

S. enterica

Question 2

Where is salmonella found?

Answer 2

GI tract of animals.

not found in human flora

Question 3

What does Salmonella produce or not produce?

Answer 3

don’t ferment lactose

produce H2S

Question 4

What are Ag associated with Salmonella

Answer 4

O, H, capsular Vi

Question 5

What kind of growth is seen with Salmonella?

Answer 5

Facultative intracellular growth

Question 6

What is the most common cause of food borne infections?

Answer 6

Salmonella

Question 7

What are diseases caused by Salmonella

Answer 7

Gastroenteritis
Typhoid (s. typhi - in humans)
Bacteremia
Osteomyelitis
Meningitis

Question 8

What are two strains of S. enterica responsible for typhoid (enteric) fever?

Answer 8

S. typhi

S. paratyphi

Question 9

What does gastroenteritis that is food-borne and caused by salmonella indicate?

Answer 9

Hard to develop immunity

Question 10

common symptoms of typhoid

Answer 10

fever

skin rash with rose-colored spots

Question 11

Where does typhoid start? then where does it spread?

Answer 11

start: SI through Peyer’s patches

then to: portal circulation – phagocytes (Macs) of liver, gallbladder, spleen

Question 12

Where is salmonella able to survive in the host?

Answer 12

phagosomes in phagocytic cells-carrier state

Question 13

How is typhoid fever transmitted?

Answer 13

Only by humans

Question 14

Three outcomes of typhoid fever

Answer 14

1. Diarrhea (SI)
2. Cholecystitis (gallbladder - carrier state)
3. Septicemia – fever

Question 15

The only reservoir of typhi

Answer 15

Humans

Question 16

What are the causes of:
enterocolitis
septicemia

Answer 16

• chicken to humans (high infection dose)

- underlying chronic disease

Question 17

Spread and Multiplication

salmonella

Answer 17

fecal-oral route

multiply in lamina propria

Question 18

Where can typhoid bacilli multiply?

Answer 18

Macrophages