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PoD 2 > Mechanisms of Resistance > Flashcards

Mechanisms of Resistance Flashcards

1
Q

Penicillins/Cephalosporins

A

B-lactamses
PBP changes
Porin channel changes

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2
Q

AMG

A

Enzyme inactivating

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3
Q

Macrolides

A

Methyltransferases that alter drug binding sites on 50 S ribosomal subunit

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4
Q

Tetracyclines

A

Transport systems that pump drugs out of the cell

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5
Q

sulfonamides

A

Increased PABA formation

Target enzyme sensitivity

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6
Q

Fluoroquinoloes

A

Target enzyme changes

Drug efflux

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PoD 2 (14 decks)

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