Mycoplasma Flashcards

1
Q

Whats unique abt mycoplasma

A

no cell wall

sterols in cell membrane

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2
Q

What is the oxygen requirement for M. pneumonia? rest of Mycoplasma?

A

strict AEROBE

rest: facultative anaerobe

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3
Q

What binds glycoprotein receptors of base of cilia of epi cells? whats the result?

A

Terminal adhesion protein (p1)

ciliostasis – > destruction of ciliated epi cells –> upper airways don’t get cleared and LOWER resp tract becomes contaminated and irritated

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4
Q

M. pneumoniae acts as what? what does it stimulate?

A

super antigen

inflammatory cells for TNF, IL1,IL6 release

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5
Q

what is the common age group?

A

5-15 yo

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6
Q

Clinical syndromes

A
Mild URTI
Otitis media
tracheobronchitis
Pneumonia
Stevens-Jonhsons syndrome
Erythema multiforme
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7
Q

How useful is micrscopes and cultures for diagnosis?

A

limited value - no cell wall

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8
Q

Best method for diagnosis?

A

Paired sera (IgM and IgG)

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9
Q

What might be useful to treat severe pulm disease, steven johnsons, encephalitis, hemolytic anemia

A

steroids

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