Spread And Growth Flashcards
What is the primary pathogen responsible for gonorrhoea?
Neisseria gonorrhoeae
What percentage of gonorrhoea infections can lead to disseminated disease?
0.5-3%
What are the common presentations of gonorrhoea in males?
Acute urethritis, dysuria, purulent discharge
What are the common presentations of gonorrhoea in females?
Endocervical infection, vaginal discharge, sometimes dysuria
What complications can arise from untreated gonorrhoea in females?
Pelvic inflammatory disease, sterility
What is the role of adhesion proteins in pathogenicity?
Attachment to host tissues
What is a key feature of Neisseria gonorrhoeae that allows it to cause infection?
Number of virulence factors
What are the portals of entry for pathogens?
Skin, mucous membranes, respiratory tract, gastrointestinal tract, genitourinary tract
Fill in the blank: The main agent in dental caries is _______.
Streptococcus mutans
What is glucan in relation to Streptococcus mutans?
Insoluble polymers of glucose
What structure extends from the surface of the bacterial cell and helps in adhesion?
Glycocalyx
Which protein receptor does Neisseria gonorrhoeae use to attach to uroepithelial cells?
Opa
What mechanism does Helicobacter pylori use to survive in the stomach?
Neutralises acid using urease
What is the primary defence mechanism of the urinary tract against infections?
Flushing of urine
True or False: Staphylococcus aureus modifies muramic acid in its peptidoglycan layer to evade lysozyme.
True