Epidemiology Flashcards

1
Q

Who conducted the first epidemiology study related to cholera?

A

John Snow

John Snow’s studies in 1849 and 1854 identified the Broad Street water pump as a source of cholera infection.

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2
Q

What is the definition of an endemic disease?

A

A disease that maintains a steady, but low frequency and at moderately regular intervals within a geographic area.

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3
Q

What does the term epidemic refer to?

A

A disease that has a sudden increase in occurrence above an expected level.

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4
Q

What is the key goal in managing outbreaks?

A

Break the chain of transmission.

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5
Q

What are the three main strategies for managing outbreaks?

A
  • Eliminate source
  • Break the link
  • Immunisation
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6
Q

Define incidence in epidemiology.

A

The number of new cases over a certain time period.

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7
Q

How is mortality rate calculated?

A

Number of deaths due to a given disease / Size of the total population with the same disease per 100,000 persons or as %.

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8
Q

What is the definition of prevalence in epidemiology?

A

The total number of individuals infected within a population at any one time.

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9
Q

What is an outbreak of disease?

A

A sudden unexpected occurrence of a disease usually focused about a limited segment of the population.

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10
Q

Identify two types of epidemics.

A
  • Common source epidemic
  • Host-to-host epidemic
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11
Q

What factors affect the susceptibility of a population to infection?

A
  • Age
  • Sex
  • Nutritional status
  • Immunological status
  • Social behaviour
  • Previous exposure
  • Environmental factors
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12
Q

What are reservoirs of infection?

A
  • Animals
  • Water and soils
  • Biting arthropods
  • Humans
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13
Q

What is the difference between communicable and non-communicable diseases?

A

Communicable diseases can be easily transmitted, while non-communicable diseases cannot.

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14
Q

Fill in the blank: The capability of being easily communicated or transmitted is known as _______.

A

[communicability]

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15
Q

What defines a pandemic disease?

A

An increase in disease occurrence within a large population over a very wide region.

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16
Q

Provide an example of a pandemic.

A
  • 1918 Spanish Flu
  • 2009 Swine Flu
  • 2019 Covid-19
17
Q

What is the incubation period in the context of infectious diseases?

A

The time between exposure to the infection and the appearance of symptoms.

18
Q

True or False: The mortality rate is the incidence of death in a population due to a particular disease per unit of time.

A

True

19
Q

What is the significance of Robert Koch in epidemiology?

A

Confirmed Vibrio cholera as the infectious agent and developed Koch’s postulates.

20
Q

What is a sporadic disease?

A

A disease which occurs occasionally and at irregular intervals within a human population.

21
Q

What are the periods of disease progression?

A
  • Incubation period
  • Prodromal period
  • Period of illness
  • Period of decline
  • Period of convalescence
22
Q

What was the outcome of the removal of the Broad Street water pump?

A

Cases of cholera went down.

23
Q

What is the importance of treating sewage in outbreak management?

A

It helps to eliminate the source or reservoir of infection.

24
Q

What is the relationship between prevalence and incidence?

A

Prevalence is the total number of cases at a given time, while incidence is the number of new cases over a certain period.

25
Q

Fill in the blank: The total number of deaths from tuberculosis in one year was 10,000, with a total number of infected individuals of 40,000. The mortality rate would be = _______.

A

[25%]