Spirochetes Flashcards
Craig be kind plz
Saprophytic
Organism that survives by eating dead cells
Spirochetes are gram…
negative
3 stages of T. pallidum infection
Primary syphilis - painless chancre typically on genitals
Secondary - rash and eruptions, wart like lesions
Tertiary - vascular and neurologic manifestations
Primary syphilis
Most contageous, appears 10-90 days after exposure as a painless ulcer on any site used for sexual activity, disappears in 4-6 weeks
Secondary syphilis
Maculopapular rash on palmar and plantar regions, condyloma latum (wart like),
Latent syphillis
Serologically positive but symptomatically negative
Tertiary syphilis
3 types of infections, aortic damage, gummatous form, or neurosyphilis in CNS
DOC for primary and 2ndary syphilis
PCN G
Tertiary neurosyphilis treatmnet
Aqueous crystalline PCN
Borrelia burgdorferi
Causative agent of lyme disease, carried by tick bite, causes erythema chronicum migrans in early stage (bullseye rash)
3 stages of lyme disease
Early stage - localized bullseye rash (erythema chronoicum migrans)
Disseminated stage - skin lesions, CNS facial nerve deficits
Late stage - persistent infection, rarely progresses to worse
Lyme disease labs
2 tier testing, ELISA and western blot, must wait till 2nd phase but can start prescription upon ECM showing up
Lyme disease treatmnet
Doxycycline, amoxicillin, no preventative vaccine
Leptospira interrogans
Causative agent of Weil’s disease, flu like symptoms with variable clinical course, often from swimming in fresh water, canoeing, kayaking
Leptospirosis phases
Phase 1 - flu like
Phase 2 - muscle breakdown, repsiratory distress, liver failure
Severe - Weil’s disease (infectious jaundice) with renal failure, hepatits with jaundice, etc
