Fungi

Question 1

Mycelium

Answer 1

Vegetative part of a fungus, consisting of a mass of branching, thread like hyphae

Question 2

Anti fungal agents interact with all other kinds of….

Answer 2

…drugs

Question 3

Common antifungals

Answer 3

• Polyenes
• Azoles
• Echinocandins
• Nucleic acid analogs

Question 4

Candida

Answer 4

Cause of candidiasis, only really seen in immunocompromised individuals, normal colonizer of human body

Question 5

Manifestations of candida

Answer 5

Thrush, vulvovaginitis, balantitis, dermatitis

Question 6

Candida treatment

Answer 6

Polyene (amphotericin B), azoles

Question 7

Dermatophytes

Answer 7

Include tinea (ringworms) capitus - head, barbe - beard, corperus - body, pedis - feet

Question 8

Dermatophytes diagnosis

Answer 8

KOH skin scrapings, wood’s light, culture

Question 9

Dermatophytes treatment

Answer 9

Most self reslolving, azole and topical steroid

Question 10

Allergic Aspergillosis

Answer 10

Inalation of speciemtn will invade tissue causing tracheobronchial colonization, alleric bronchopulmonary aspergillosis, high eosinophilia

Question 11

Aspergillosis treatment

Answer 11

Azoles

Question 12

Invasive aspergillosis

Answer 12

Often seen in immunocompromised host, large fungus balls on tissue,

Question 13

Invasive aspergillosis treatment

Answer 13

Amphotericin B, azole, echindole

Question 14

Histoplasmosis

Answer 14

dimorphic, most common us fungal infection, birds are vector, flu like symptoms

Question 15

histoplasmosis treatment

Answer 15

azole and amphotericin B

Question 16

Coccidiomycosis

Answer 16

Highly infectious, airborn spor infection, no human to human transmission, southwestr american, acute flu like, rash, eosinophilia

Question 17

Coccidiomycosis diagnosis

Answer 17

sputum culture

Question 18

Coccidomycosis treatment

Answer 18

azoles

Question 19

Cryptococcosis

Answer 19

Encapsulated yeast, bird feces origin, general illness

Question 20

Cryptococcosis diagnosis

Answer 20

Sputum cultures, india ink stain

Question 21

Cryptococcosis treatment

Answer 21

2-4 months observation then fluconazole or amphotericin B

Question 22

Disseminated cryptococcosis

Answer 22

Meningoencephalitis

Question 23

Cryptococcosis treatment

Answer 23

Amphotericin B and flucytosone B

Question 24

Sporotrichosis

Answer 24

Dimorphic plant disease, cutaenous most of time causing raised nodule, can go systemic rarely

Question 25

Sporotrichosis treatment

Answer 25

Itraconazole, amphotericin B