Fungi Flashcards
Anna mae shrooms
Mycelium
Vegetative part of a fungus, consisting of a mass of branching, thread like hyphae
Anti fungal agents interact with all other kinds of….
…drugs
Common antifungals
- Polyenes
- Azoles
- Echinocandins
- Nucleic acid analogs
Candida
Cause of candidiasis, only really seen in immunocompromised individuals, normal colonizer of human body
Manifestations of candida
Thrush, vulvovaginitis, balantitis, dermatitis
Candida treatment
Polyene (amphotericin B), azoles
Dermatophytes
Include tinea (ringworms) capitus - head, barbe - beard, corperus - body, pedis - feet
Dermatophytes diagnosis
KOH skin scrapings, wood’s light, culture
Dermatophytes treatment
Most self reslolving, azole and topical steroid
Allergic Aspergillosis
Inalation of speciemtn will invade tissue causing tracheobronchial colonization, alleric bronchopulmonary aspergillosis, high eosinophilia
Aspergillosis treatment
Azoles
Invasive aspergillosis
Often seen in immunocompromised host, large fungus balls on tissue,
Invasive aspergillosis treatment
Amphotericin B, azole, echindole
Histoplasmosis
dimorphic, most common us fungal infection, birds are vector, flu like symptoms
histoplasmosis treatment
azole and amphotericin B
Coccidiomycosis
Highly infectious, airborn spor infection, no human to human transmission, southwestr american, acute flu like, rash, eosinophilia
Coccidiomycosis diagnosis
sputum culture
Coccidomycosis treatment
azoles
Cryptococcosis
Encapsulated yeast, bird feces origin, general illness
Cryptococcosis diagnosis
Sputum cultures, india ink stain
Cryptococcosis treatment
2-4 months observation then fluconazole or amphotericin B
Disseminated cryptococcosis
Meningoencephalitis
Cryptococcosis treatment
Amphotericin B and flucytosone B
Sporotrichosis
Dimorphic plant disease, cutaenous most of time causing raised nodule, can go systemic rarely
Sporotrichosis treatment
Itraconazole, amphotericin B
