Spina Bifida Flashcards
Spina Bifida is the most common type of ________ defect
Neural tube
_____ most common childhood abnormality/ disease causing disability after CP
2nd most common
What are Risk factors for spina bifida
Polycentric inheritance- recurrence rate 2.5%- 5% after birth of one child and doubles
environment
-Low SEC
-mid spring conception
-maternal obesity
-maternal diabetes
-anticonvusent drugs
-maternal febrile illness
-nutrition
Low folic acid deficiency contributes to spina bifida true or false
true
When does the neural tube close
weeks 3-4
Most severe both brain and spinal cord remain open
craniochischisis
Anterior (rostral) neuropore defect
anencephaly
posterior (caudal) neuropore defect
spina bifida
What is the double hit theory
maldevelopment of the neural tube + exposure to amniotic fluid= damage to normal spinal cord tissues
How is spina bifida diagnosed
Prenatal diagnosis at 18-20 weeks
Lemon shaped skull
banana sign- cerebellum is wrapped around the posterior brainstem due to downward traction of spinal cord
What are the treatments for spina bifida
post natal closure
pre natal closure
fetal surgery
fetoscopy
stem cell graft
will spina bifida present as an upper motor lesion or lower motor lesion
lower motor lesion
weakness
absent or diminished reflexes
absent babinski
flaccid bladder
Arnold chiari type 2
hydrocephalus
motor, sensory, bowel and bladder impairments
majority 75% lumbar
myelomenigocele
incomplete skin coverage= CSF leak
<10% of cases of cystica
neurologic signs may be normal
pocket w/ out nerves outside of spinal tract
meningocele
Cystic cavity anterior to spinal cord
not very commin
myelocele
50% pigmented nervus dimple dermal sinus
No neurological deficits
rarely associated with tethered cord
no neurologic or musculoskeletal changes
occulta
Neurosurgical complications occur throughout childs life
sleep apnea
palpitations
diplopia
dysphagia
arnold chiari Type 2
Neurosurgical complications occur throughout childs life
headaches
nausea
altered mental status
lethargy
personality change
vision
hoarse cry
swallow issues
hydrocephalus
motor changes
sensory changes
reflex changes
neck pain
syringomyelia
motor changes
sensory changes
reflex changes
back pain
progressive scoliosis
bowel or bladder changes
sexual changes
tethered cord- during growth spinal cord gets caught in scar tissue
impaired fine motor coordination and ataxia
severe cases may lead to respiratory dysfunction and arrhythmia due to compression of brainstem
Arnold Chiari Type II
What is the most frequent single cause of death in spina bifida
central respiratory dysfunction
sleep disordered breathing affects up to ____% of people with spina bifida
81%
usually presents at birth > symptomatic during first week
hydrocephalus
what are the sign or gaze palsy associated with severe hydrocephalus?
sunset sign or upward gaze palsy
how is hydrocephalus treated?
with a shunt, taking fluid from one area putting it somewhere else
>80% will require VP shunt with revisions
infection is most frequent followed by obstruction
fluid filled central cavity
symptoms change in motor and sensory function increased reflexes, pain
often associated with hydrocephalus so treat the hydrocephalus first
weakness in functions of the hands
temperature or sensory changes
syringomyelia