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SPET1_FC_Pharmacology Flashcards

1
Q

Epinephrine

A

alpha 1,2; beta 1,2

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2
Q

NE

A

alpha 1,2; beta 1

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3
Q

Isoproterenol

A

beta 1,2

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4
Q

Dopamine

A

alpha 1,2; beta 1,2

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5
Q

Dobutamine

A

alpha 1,2;beta 1*, 2

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6
Q

Phenylephrine

A

alpha 1,2

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7
Q

Albuterol, salmeterol, terbutaline

A

beta 1,2

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8
Q

Ritodrine

A

beta 2

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9
Q

Epinephrine

A

anaphylaxis, glaucoma (open angle), asthma, hypotension

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10
Q

NE

A

Hypotention (decreased renal profusion)

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11
Q

Isoproterenol

A

Torsade de points, bradyarrhythmias (can worsen ischemia)

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12
Q

Dopamine

A

Shock (renal profusion), HF, inotropic and chronotropic

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13
Q

Dobutamine

A

HF, cardic stress testing; inotropic and chronotropic

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14
Q

Phenylephrine

A

hypotention (vasoconstrictor), ocular procedure (mydriatic), rhinitis (decongestant)

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15
Q

Albuterol, salmeterol, terbutaline

A

acute asthma (metaproterenol and albuterol); long-term asthma or COPD (salmeterol); reduce premature uterine contrations (terbutoline)

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16
Q

Ritodrine

A

reduce premature uterine contrations

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17
Q

acetaminophen

A

N-actylcysteine (replinish gluthione)

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18
Q

Salicylates

A

NaHCO3 (alkalinize urine)

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19
Q

Amphetamines (basic)

A

NH4CL (acidify urine)

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20
Q

Actelcholinesterase inhibitors, organophosphates

A

atropine, pralidoxime

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21
Q

Antimuscarinic, anticholinergic agents

A

physostigmine salicylate, control hyperthermia

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22
Q

beta blockers

A

glucagon

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23
Q

digitalis

A

normalize K, Liocaine, Anti-dig Fab, Mg2+

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24
Q

Iron

A

DeFEroaxamine, deFErasirox

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25
Lead
CaEDTA, dimercprol, succimer
26
Mercury, arsenic, gold
Dimercaprol (BAL), succimer
27
Copper, arsenic, gold
Penicillamine
28
Cyanide
Nitrite + thiosulfate, hyroxocobalamin
29
Methemoglobin
Methylene blue, vitamin C
30
CO
100% O2, hyperbaric O2
31
Methanol, ethlylene glycol (antifreeze)
Fomepizle> ethanol, dialysis
32
Opioids
Naloxone/naltrexone
33
Benzodiazepines
Flumazinil
34
TCAs
NaHCO3 (plasma alkalinization)
35
Heparin
Protamine
36
Warfarin
Vitamin K, FFP
37
tPA, streptokinase, urokinase
Aminocaproic acid
38
Theophylline
beta blocker
39
Caronary Vasospasm [cause]
cocaine, sumatriptan, ergot alkaloids
40
Cutaneous Flushing [cause]
vancomycin, adenosine, niacin, Ca2+ channel blockers
41
Dilated Cardiomyopathy [cause]
Doxorubicin (adriamycin), daunorubicin
42
Torsades de pointes [cause]
Class III (sotalol) and Class IA (quinidine) antiarrhthmics
43
Agranulocytosis [cause]
clozapine, carbamazepine, colchicine, prophylthiouricil, methimazole, daspone
44
Aplastic anemia [cause]
chloramphinenicol, benzene, NSAIDs, propylthiouracil, Methimazole
45
Direct Coombs-positive hemolytic anemia [cause]
Methyldopa, penicillin
46
Grey baby syndrome [cause]
chloramphenicol
47
Hemolysis in G6PD-deficient patients [cause]
Isoniazid (INH), sulfanamides, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin
48
Megaloblastic anemia [cause]
Phenytoin, Methotrexate, Sulfa drugs
49
Thrombotic complications [cause]
OCPs
50
Cough [cause]
ACEi
51
Pulmonary Fibrosis [cause]
Bleomycin, amiodarone, busulfan
52
Acute, cholestatic hepatits, jaundice [cause]
Erythromycin
53
Focal to massive hepatic necrosis [cause]
Halothane, Amanita phalloides, Valproic acid, Acetaminophen
54
Hepatitis [cause]
Isoniazid
55
Pseudomembranous colitis [cause]
Clindamycin, ampicillin
56
Adrenal insufficiency [cause]
GC withdrawel (HPA suppression)
57
Gynecomastia [cause]
Spirinolactone, digitalis, cimitidine, chronic alcholol use, estrogens, ketoconazole
58
Hat flashes [cause]
tamoxifen, clomiphene
59
Hyperglycemia [cause]
niacin, tacrolimus, protease inhibitors, HCTZ, corticosteroids
60
Hypothyroidism [cause]
Lithium, amiodarone, sulfonamides
61
Fat redistribution [cause]
GC, PI
62
Gingival hyperplasia [cause]
Phenytoin, verapamil
63
Gout [cause]
Furosemide, thiazides, niacin, chyclosporine
64
Myopathies [cause]
Fibrates, niacin, colchine, hydroxychloroquine, Interferon-alpha, penicillamine, statin, GC
65
Osteoporosis [cause]
Corticosteroid, heparin
66
Photosensitivity [cause]
Sulfonamides, amiodarone, tetracyclin
67
Rash (SJS) [cause]
Penicillin, ethosux, carbamazepine, sulfa drugs, lamotrigine, allopurinol, phenytoin, phenobarbital
68
SLE-like sydrome [cause]
hydralazine, isoniazid, procaainamide, phenytoin
69
Teeth (kids) [cause]
tetracyclines
70
Tedonitis, tendon rupture, and cartilage damage [cause]
Fluoroquinolones
71
DI [cause]
Lithium, demeclocycline
72
Fanconi's syndrome [cause]
EXPIRED tetracycline
73
Hemorrhagic cystisi [cause]
cyclophosphamide, ifosfamide (prevent by coadministering with mensa)
74
Interstitial nephritis [cause]
Methicillin, NSAIDs, furosemide
75
SIADH [cause]
Carbamazipine
76
Cinhoncism [cause]
Quinidine, quinine
77
Parkinson-like syndrome [cause]
Antipsychotics, reserpine, metoclopramide
78
Seizures [cause]
Isoniazid, Bupropion, Imipenem/cilastatin, tramadol, Enflurane, Metoclopramide
79
Tardive dyskenisia [cause]
Antisychotics
80
Antimuscarinic [cause]
Atropine, TCAs, H-blockers, neuroleptics
81
Disulfiram-like rxn [cause]
Metronidazole, certain cephalosporins, procabazine, 1st generation sulfonylureas
82
Nephrotoxicity/ototoxicity [cause]
Aminoglycosides, vancomycin, loop diuretics, cisplatin
83
P 450 (+) Inducers
Modafinil, Barbituates, St. John's Wart, Phenytoin, Rifampin, Griseofulvin, Carbamazepine, Chronic alcohol use
84
P 450 (-)
macrolids, Amiodarone, Grapefruit juice, Isoniazid, Cimetidine, Ritonavir, Acute alcohol abuse, cirpofloxacin, ketoconazole, sulfonamides, gemfibrozil, quinidine

STEP1 (13 decks)

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