Specific Immune Responses Flashcards
Which of the following concerning IgG is FALSE?
A. IgG crosses the placenta
B. IgG enhances opsonization
C. IgG is the most common antibody in serum
D. IgG is a pentamer
E. IgG is mainly seen in the secondary immune system
D
B cells mature in the bone marrow and are very effective against intracellular pathogens. True or false?
False
What is the difference between innate and adaptive?
innate: no memory; adaptive: memory
innate: any pathogen; adaptive: specific
What is the difference between antigens and antibodies?
Antigen: foreign substance that stimulates immune response
antibodies: binds to the antigen that it came from + prevents spread
What are the two most important cells for specific responses?
T cells and B cells
What does it mean when a T/B cell is mature?
it has the receptor to recognize antigens
What is the difference between T and B cells?
T: Mature in the thymus; works against Intracellular pathogens
B: Mature in the bone marrow ; Mainly work against extracellular pathogens
What are the four types of adaptive immunity?
- naturally active
- naturally passive
- artificially active
- artificially passive
What is the difference between naturally acquired active and passive immunity?
active- exposure of pathogen
passive- antibodies passed from mother to fetus
What is the difference between artificially acquired active and passive immunity?
Active- prepared antigen
Passive- prepared antibodies
What is the structure of antigens?
large
proteins/amino acids
What is the structure of antibodies?
proteins
produced by B cells after activation
secreted by plasma cells
Two identical heavy (green) and light chains (blue)
Y- shaped
What is the structure of antigen-binding sites?
Two antigen-binding sites (for one antibody, one on the left, one on the right)
Where do antibodies go?
On the antigen-binding cites, NOT inside the cell
What are the five classes of antibodies?
IgM
IgG
IgA
IgD
IgE
