DNA Viral Families

Question 1

What is the only ssDNA family?

Answer 1

Parvoviridae

Question 2

What virus comes from the Papovaviridae family and what does it cause?

Answer 2

HPV and cervical cancer, causes warts

Question 3

What diseases are caused from Poxviridae?

Answer 3

Smallpox and Monkeypox

Question 4

What is the only disease that has been fully eradicated?

Answer 4

Smallpox

Question 5

What is the structure of Poxviridae? (ds or ss, shape, etc.)

Answer 5

ds, complex, enveloped

Question 6

What does Hepadnaviridae cause?

Answer 6

Hepatitis B

Question 7

What is the structure of Herpesviridae? (ds or ss, shape, etc.)

Answer 7

ds, icosahedral, enveloped

Question 8

What are the two most famous diseases from Herpesviridae?

Answer 8

HHV-1 (cold sores) and HHV-2 (genital herpes)

Question 9

What does HHV-3 cause?

Answer 9

Chickenpox/Shingles

Question 10

Why is Herpesviridae unique from other viruses?

Answer 10

It’s latent (can’t be cured, will lie dormant in nerve ganglia, and can be reactivated)

Question 11

Where does HHV-2 lie dormant and how is it reactivated?

Answer 11

In the trigeminal nerve ganglia and travels down the nerve a few days before the cold sore appears. Lies dormant in sacral nerve ganglia for genital herpes.

Can be reactivated by stress, immunosuppression, hormonal changes, pregnancy, etc.

Question 12

Which of the following is a family of viruses that has ds DNA, is enveloped, and causes latent infections?
A. Poxviridae
B. Orthomyxoviridae
C. Coronoviridae
D. Herpesviridae
E. Parvoviridae

Answer 12

D

Question 13

What is the structure of Parvoviridae?

Answer 13

ssDNA, icosahedral, naked

Question 14

What is the structure of Adenoviridae?

Answer 14

dsDNA, icosahedral, naked

Question 15

What is the structure of Papovaviridae?

Answer 15

dsDNA, icosahedral, naked

Question 16

What are the three species from the Papovaviridae family and what do they cause?

Answer 16

PA: papilloma = warts
PO: polyoma = tumors
VA: vacuolating = vacuoles in host cell

Question 17

What is the structure of Poxviridae?

Answer 17

dsDNA, complex, enveloped, very large

Question 18

What is the structure of Hepadnaviridae?

Answer 18

circular dsDNA, icosahedral, enveloped
also has an unusual replication cycle

Question 19

What is the structure of Herpesviridae?

Answer 19

dsDNA, icosahedral, enveloped, very large and latent

Question 20

What does Hepadnaviridae cause?

Answer 20

hepatitis B virus

Question 21

What does Poxviridae cause?

Answer 21

smallpox and cowpox

Question 22

What does Papovaviridae cause?

Answer 22

warts, tumors (mostly warts)

Question 23

What does Adenoviridae cause?

Answer 23

respiratory diseases

Question 24

What does Parvoviridae cause?

Answer 24

gastroenteritis, fetal death, fifth disease

Question 25

Which virus causes 85% of cold sores? How is it spread?

Answer 25

HHV-1 Spread via touch and contaminated items such as towels and eating utencils

Question 26

What does HHV-2 cause?

Answer 26

Genital herpes -> vesicular rashes

Question 27

How are herpes reactivated?

Answer 27

1. Lies dormant in trigeminal or sacral ganglia 2. Activated via stress, hormonal changes, etc. 3. Virus travels down the nerve to the mouth or genitals 4. Cold sores/herpes develops

Question 28

What does HHV-3 cause?

Answer 28

chickenpox and shingles