Specific Antidotes pg 252 Flashcards by Logan Adams

Q

Acetaminophen

A

N-acetylcystein (replenishes glutathione)

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Q

AchE inhibitors & Organophosphates

A

Atropine followed by Pralidoxime

Pralidoxime regenerates AchE

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Q

Amphetamines (basic)

A

NH4Cl: acidifies urine

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Q

Antimuscarinics & Anticholinergic Agents

A

Physostigmine salicylate & control hyperthermia

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Q

Benzodiazepines

A

Flumazenil

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Q

Beta-Blockers

A

Glucagon, Atropine, Calcium (inc HR)

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Q

Carbon Monoxide

A

100% Oxygen, Hyperbaric Oxygen

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Q

Copper/Arsenic/Gold

A

Penicillamine

*think what treats Wilson’s dz

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Q

Cyanide

A

Nitrite + Thiosulfate, Hydroxocobalamin

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Q

Digitalis

A

Anti-dig Fab fragments + correct electrolytes (K and Mg)
If bradycardia, Atropine
If tachycardia, Lidocaine

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Q

Heparin

A

Protamine Sulfate

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Q

Iron

A

Deferoxamine or Deferasirox

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Q

Lead Tox in Adults

A

EDTA + Succimer

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Q

Lead Tox in Children

A

EDTA, Dimercaprol, Succimer

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Q

Mercury/Arsenic/Gold

A

Dimercaprol (BAL), Succimer

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Q

Methanol or Ethylene Glycol

A

Fomepizole > Ethanol, Dialysis

Fomepizole inhibits Alcohol Dehydrogenase

Q

Methemoglobin

A

Methylene Blue, Vitamin C

Cimetidine for slow reversal

Q

Opioids

A

Naloxone

Q

Salicylates

A

NaHCO3 (alkalinizes urine), Dialysis

Q

Tricyclic Antidepressants

A

NaHCO3 (plasma alkalinization)

Q

tPA/Streptokinase/Urokinase

A

Aminocaproic Acid

Q

Warfarin

A

Vitamin K

If active bleeding, Fresh Frozen Plasma