Autoantibodies pg 210 Flashcards

1
Q

Anti-Ach receptor

A

Myasthenia Gravis

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2
Q

Anti-Basement membrane

A

Goodpasture’s

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3
Q

Anti-Cardiolipin, Lupus Anticoagulant

A

SLE, Antiphospholipid syndrome

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4
Q

Anti-Centromere

A

Limited Scleroderma aka CREST syndrome

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5
Q

Anti-desmoglein

A

Pemphigus Vulgaris

Note: Staph aureus toxins also target desmoglein in Staph Scalded Skin Syndrome

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6
Q

Anti-Smith

A

SLE

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7
Q

Anti-dsDNA

A

SLE specifically Lupus Renal Dz

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8
Q

Anti-Glutamate decarboxylase

A

Type 1 Diabetes Mellitus

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9
Q

Anti-Hemidesmosome

A

Bullous Pemphigoid

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10
Q

Anti-Histone

A

Drug-induced Lupus

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11
Q

Anti-Jo-1, Anti-SRP, Anti-Mi-2

A

Polymyositis, Dermatomyositis

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12
Q

Anti-Microsomal, Anti-Thyroglobulin

A

Hashimoto Thyroiditis

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13
Q

Anti-Mitochondrial

A

Primary Biliary Cirrhosis

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14
Q

Sensitive Ab for SLE

A

ANA

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15
Q

Anti-Scl70 (Anti-DNA topoisomerase I)

A

Diffuse Scleroderma

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16
Q

Anti-Smooth Muscle

A

Autoimmune Hepatitis

17
Q

Anti-SSA/B (Anti-Ro/La)

A

Sjogren’s

18
Q

Anti-TSH receptor

A

Graves

19
Q

Anti-U1RNP

A

Mixed Connective Tissue Dz

20
Q

c-ANCA (PR3-ANCA)

A

Wegener’s aka WeCener’s

21
Q

IgA anti-endomysial or IgA anti-tissue transglutaminase

A

Celiac’s

22
Q

p-ANCA (MPO-ANCA)

A

Microscopic Polyangiitis

Churg-Strauss syndrome

23
Q

Ab which is most commonly IgM that is specific to IgG Fc region.

A

Rheumatoid Factor

24
Q

Rheumatoid Factor

A

RA

25
Q

Anti-CCP

A

RA