Special Species Flashcards

1
Q

Most tiny animals have (high/low) metabolic rates

A

High

Mouse HR: 300-800
Mouse Resp: 100-200

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2
Q

Should you fast special species before anesthesia ?

A

No

Predisposed to hypoglycemia due to fast metabolic rates

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3
Q

Why are small animals predisposed to hypothermia?

A

Lose heat quickly because they have high body SA : weight ratio

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4
Q

T/F: mice and rabbits are obligate nasal breathers

A

True

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5
Q

What are indicators of stress in lab animals?

A
Lack of grooming 
Hunched posture 
Decreased appetite or activity 
Aggression 
Vocalization
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6
Q

What are common routes of anestheric administration in lab animals ?

A

Intraperitoneal
Subcutaneous
Inhalational

IV

  • mice and rat: tail vein
  • rabbit: auricular or cephalic
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7
Q

What injectable anesthetic is most commonly used in lab animals

A

Ketamien

-combine with A2 agonsits or midazolam

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8
Q

How does the dosage in lab animals compare to other species?

A

Much higher dosages required in small animals due to hypermetabolic state

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9
Q

What agents are used for sedation in lab animals?

A

A2 agonist
-dexmedetomidine or xylazine

Benzodiazepines
-midazolam

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10
Q

What are the injectable induction agents in lab animals?

A

Ketamine with A2 agonists

Alfaxalone

Propofol

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11
Q

How do you intubate lab animals?

A

Very hard- mostly not performed

Small ET tub 2/3mm

  • blind
  • fiberoptic-guided
  • otoscope-guided
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12
Q

What type of breathing circuit is used in lab animals?

A

Small volume, non-rebreathing (has minimal resistance )

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13
Q

Opioids used in lab animals?

A

Buprenorphine

Butorphanol

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14
Q

NSAIDS used in lab animlas?

A

Carprofen

Meloxicam

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15
Q

How can you ensure good recovery in lab animals?

A
Continue monitoring 
Warmth 
Fluids 
Food 
Analgesia
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16
Q

What can cause prolonged anesthetic recovery in ectotherms?

A

Body temperature

-> low temp-> low metabolism

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17
Q

What is the structure of the cardiopulmonary system in ectotherms?

A

3chambered heart (lizards, chelonians, and snake)

2 atria and 1ventricle

Systemic arterial BP is generally Lowe

18
Q

T/F: IM injections in the hindlimbs are the best method of medication in ectotherms?

A

False

AVOID IM injections in caudal body parts as they may cause nephrotoxicity / are rapidly excreted

Dual bloody supply to kindly -> renal portal system

19
Q

What type of ETT tube should be used in ectotherms?

A

Uncuffed - like birds, ectotherms have complete cartilage rings

20
Q

T/F: Ectotherms do not have a diaphragm, therefore the intercostal, pectoral, and abdominal muscles are used to facilitate breathing

21
Q

How should you restrain a snake?

A

Behind the head and then the rest of the body

For venomous snakes, use hoo/tongs and place head in non=permeable container

22
Q

In what type of snake can you intubate, and why would this be better than gas anesthetics?

A

Nonvenomous snakes

Faster induction

23
Q

What are the injectable anestherics used in snakes?

A

Ketamine (30min induction, 2hr-2day recovery)

Medetomidine
-reverse with atipamezole

24
Q

In turtles/tortoises, their shell wis about 50% of their body mass. If you include their body mass in your calculations for drugs, do you used the high or low range of the dose

A

Low range

-shell is biologically inactive

25
What are the drugs used in turtles along with their challenges?
Ketamine (IM) -long recovery Propofol (IV) Gas anesthesia - will hold breath and as a result take long to be anesthetized
26
How are crocodiles immobilized?
Trap/snare Then injection - ketamine and medetomidine (partially reversible) - succinylcholine - gallamine Do not dart in water—> drowning
27
Succinylcholine MOA?
Depolarizing neuromuscular blocker - depolarize muscle fiber and make it resistant to further stimulation by ACh
28
Is succinylcholine reversible
Nope Diffuses out of synapse over time
29
Succinylcholine can be combined with _________________To reduce stress
Diazepam
30
Gallamine MOA
Competitive non-depolarizing neuromuscular agent -> blocks binding of ACh receptor
31
Does gallamine provide any analgesia?
Nope Paralytic - animal is still concours and feels pain
32
Is gallamine reversible?
Yes | Neostigmine —> inhibits acetylcholinesterase —> ACh increases and competes with gallamine for ACh
33
What can you use to reverse neostigmine in case you have overdosed and have excessive parasympathetic stimulation?
Atropine/glycopyrolate
34
Excessive handling can make the crocodile prone to??
Stress and myopathy
35
How should crocodiles recover from anesthesia
Placed on dry land, facing water Depending on restraint method, may take up to 2hrs to recover
36
What is the fasting time for frogs and toads?
None | Fasting is not necessary
37
What are the anesthesia options for frogs and toads?
MS-222 immersion Topical application of sevoflurane or isoflurane in KY jelly Injectables - ketamine and A2 agonsit (associated with high mortality)
38
What is the fasting time for fish undergoing anesthesia?
12-24hrs | -risk of regurgitation
39
What are the anesthesia options in fish?
MS-222 immersion | Inhalation anesthetic flow-by
40
How can you monitor anesthetic depth in fish?
Jaw tone Righting reflex Heartbeat can be visualized Gill movements for respiration
41
What do you do for recovery of fish from anesthesia ?
Transfer to aerated anesthetic-free recovery tank/chambers