Special senses Flashcards

1
Q

What are the General senses receptors?

A
  • Chemoreceptors
  • Mechanoreceptors
  • Thermoreceptors
  • Nociceptors
  • PHOTORECEPTORS→melanocytes found to contain rhodopsin, which responds to light
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2
Q

What are the Special senses receptor types?

A
  • Chemoreceptors
  • Mechanoreceptors
  • Photoreceptors
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3
Q

What is the purpose/what are Receptors?

A
  • In order to detect a stimulus, there must be a receptor –
    something to receive the information
  • Receptors are:
  • Sensory nerve endings or
  • Specialized cells adjacent to sensory nerves
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4
Q

What are sensory pathways?

A
  • A stimulus (light, sound, taste, etc) generates a receptor
    potential
  • Receptor potentials can be weak or strong, unlike action
    potentials which are all-or-none
  • The receptor potential triggers an action potential in the sensory nerve
  • Action potential travels to the brain where it is ”sensed”
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5
Q

What are Mechanoreceptors?

A

Mechanoreceptors: detect changes in pressure or movement;
-Ex. pressure receptors in skin, proprioceptors in muscles and joints

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6
Q

What are Thermoreceptors?

A

Thermoreceptors: detect temperature change

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7
Q

What are Nociceptors?

A

Nociceptors: detect pain

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8
Q

What are Chemoreceptors?

A

Chemoreceptors: detect changes in chemical concentrations;
- Ex. taste buds and olfactory receptors

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9
Q

What are Photoreceptors?

A

Photoreceptors: detect light energy;
-Ex. the eye

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10
Q

Where are special senses located?

A

*Special senses are localized and confined to the head region
- The receptors are specialized receptor cells

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11
Q

How is Taste (Gustation) recepted?

A
  • Taste receptors are found taste buds in the mucosa of the mouth and pharynx
  • Taste buds are found on tongue, posterior palate, pharynx, inside of cheeks, posterior wall of pharynx, and the epiglottis
  • Most taste buds are found in papillae on tongue
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12
Q

What are the types of the papillae that contain taste buds?

A

Papillae that contain taste buds:
* Vallate (circumvallate) papillae
- Inverted “V” on back of tongue
* Fungiform papillae
- Scattered throughout surface of tongue
* Foliate papillae
- Posterolateral surface of tongue

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13
Q

What are the components of taste buds?

A

*Each papilla has many taste buds (except filiform papillae)
*Each taste bud is made of 50-100 epithelial cells:
- Gustatory epithelial cells (taste)
– Have long microvilli called gustatory hairs that extend through taste pore
- Basal epithelial cells (replace old and damaged cells every 7-10 days)

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14
Q

What are the components of taste?

A

*Dissolved molecules in saliva enter taste pore
*Molecules bind to receptors on gustatory hair cells
*Action potentials are generated, sensory neurons stimulated, signals sent to CNS
*Types of tastes:
- Sweet
- Sour
- Salty
- Bitter
- Umami
*These different tastes occur all over the tongue (taste map is incorrect)

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15
Q

How do smell and taste work together?

A

*Flavor = combination of taste, smell, and texture
*Smell and taste work hand-in hand
- Food has less taste when you have a cold
- Good smells stimulate appetite; bad smells do not

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16
Q

What is the Gustatory Pathway in brain?

A

*Taste receptors→sensory nerve fibers in cranial nerves →brainstem →thalamus →gustatory cortex (insula)

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17
Q

What is Olfaction (Smell)?

A

*Olfactory receptors are in the olfactory epithelium (pseudostratified columnar) that covers superior nasal concha and the superior part of nasal septum
*Millions of bipolar neurons = olfactory sensory cells
*Olfactory stem cells
- Continually form new olfactory sensory neurons

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18
Q

What are the components of Olfactory Receptors?

A
  • Each bipolar olfactory neuron
  • Has an apical dendrite that is near surface of epithelium
    – Has olfactory cilia (hairs)—location of chemoreceptors
  • Mucus traps and dissolves molecules from inhaled air
  • Chemical binds to chemoreceptor and activates olfactory sensory neuron
  • Extensions of sensory neurons = filaments of olfactory nerve
  • Enter CNS through cribriform plate of ethmoid bone
  • Synapse with mitral cells in olfactory bulb at glomeruli
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19
Q

What is olfaction?

A

*Extensions from mitral cells relay olfactory information via olfactory tract to
1. Limbic system
- Smells elicit emotions and memories
2. Primary olfactory cortex in temporal lobe

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20
Q

What is Chemical Sense Disorders?

A

Olfactory disorders are most common (compared to taste disorders)
* Anosmia = absence of smell
- Blow to head/whiplash
- Colds/allergies
- Zinc deficiency
* Uncinate fits = olfactory hallucinations
- Brain disorders

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21
Q

Components of vision?

A

Vision
*Humans use vision as our dominant sense
*70% all sensory receptors in our body are located in our eyes

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22
Q

What are the Accessory Structures of the Eye?

A
  • Eyebrows
    • Shade eyes from sunlight
    • Prevent sweat from running into eyes
  • Palpebrae = eyelids
    • Have eyelashes at free margin
      – Keep foreign objects out of eye
      – Very sensitive→blinking reflex
    • Sebaceous glands in palpebrae
      –Lubricate surface of eye
      – Those associated with eyelashes can get infected = sty
  • Palpebral fissure
    • Space between eyelids
  • Lacrimal caruncles
    • Pink raised portion; medial angle
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23
Q

Surface Anatomy of the Eye?

A

Conjunctiva
* Transparent mucous membrane
* Covers inner surface of eyelids and anterior surface of eyeball (except cornea)
* Conjunctivitis (very contagious)

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24
Q

Tear Production

A

Lacrimal apparatus is made of the lacrimal gland and ducts that drain lacrimal fluid
* Lacrimal gland
- Superolateral region of the orbit
- Serous cells produce lacrimal fluid = tears
– Contains mucus, antibodies, and lysozyme (destroys bacteria)
- Fluid washes irritants away from eye surface

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25
Q

Tear Drainage

A

Tears move across eye, enter puncta
* Drain into lacrimal canaliculi, then
* Lacrimal sac →
* Nasolacrimal duct →
* Nasal cavity

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26
Q

What is the Extrinsic Eye Muscles?

A

*Movement of each eye is controlled by 6 extrinsic eye muscles
*Skeletal muscles
*Attach to outer surface of the eyeball (sclera)

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27
Q

What is Strabismus?

A

*Strabismus = misaligned eyes (cross-eyed)
*Caused by a problem with one or more of extrinsic eye muscles
*Eyes do not align properly
*Some results:
- Double vision
- Lack of stereoscopic (3-D) vision
- Amblyopia (reduced vision in the weaker eye “lazy eye”)

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28
Q

What are the layers of the eye?

A

3 tunics (= layers)
*Fibrous tunic (outermost)
*Vascular tunic
*Sensory tunic (innermost)

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29
Q

What is the Fibrous Tunic?

A

*Outermost layer
*Extension of dura mater
*Provides protection and mechanical support
*Avascular
*Parts
- Sclera (dense irregular CT→opaque)
- Cornea (dense regular CT→transparent)
*Sclera is covered by conjunctiva
- Mucous membrane (stratified columnar with goblet cells)

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30
Q

What is Vascular Tunic?

A

*Middle tunic
Parts
* Choroid: vascular, dark surface absorbs excess light
* Iris is made of smooth muscle
- Contracts and enlarges to regulate light entry to eye ball →pupil changes size
- Melanocytes (brown pigment, eye color)

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31
Q

What makes eyes darker in color?

A

Darker colored eyes have more pigment in anterior region of iris. Light eyes have little to no pigment in the anterior region.

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32
Q

What is the ciliary body of the Vascular Tunic?

A

Ciliary body
* Ciliary muscle
- Smooth muscle
*Suspensory ligaments
*Controls the shape of the lens (which focuses light onto the back surface of the eye)
*Capillaries within produce aqueous humor

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33
Q

What is Accommodation?

A
  • The lens changes shape when looking at things up close = accommodation
  • Close objects (parasympathetic control)
    • Ciliary muscle contracts
    • Suspensory ligaments slacken
    • Lens becomes round
  • Distant objects (sympathetic control)
    • Ciliary muscle relaxes
    • Suspensory ligaments become taut
    • Lens is flattened
  • With age, the lens becomes less elastic →presbyopia
    - Bifocals or reading glasses are needed
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34
Q

What is Sensory Tunic?

A

*Innermost tunic
*Two layered structure:
1. Pigmented layer (next to choroid)
* Single epithelial layer, contains melanin granules
* Absorbs light
* Nourishes neural layer
2. Neural layer (in contact with lumen of eye)
* Three types of neural cells
- Photoreceptor cells
- Bipolar cells
- Ganglion cells

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35
Q

What are Rods of the Neural Layer of Retina?

A

Photoreceptors (activated by light)
*Rod cells
- Most numerous (~120 million per eye)
- Most sensitive to light (good for night vision)
- Most numerous in periphery of retina (sides)

36
Q

What are cones of Neural Layer of Retina?

A

Photoreceptors (activated by light) = Cone cells
* Color vision
* 3 subtypes that respond to different
types of light:
- Blue light
- Red light
- Green light
* Work best in bright light (do not function well in low light)
* Concentrated in central part of retina (straight back)

37
Q

What are Bipolar cells of Neural Layer of Retina?

A

Bipolar cells
* Activated by rods and cones

38
Q

What are Ganglion cells of the Neural Layer of Retina?

A

Ganglion cells
* Activated by bipolar cells
* Axons of ganglion cells transmit impulse to brain through optic nerve

39
Q

Path way of light through retina

A

*Photoreceptors activate bipolar cells →bipolar cells activate ganglion cells →axons of ganglion cells form optic nerve →brain

40
Q

What is the purpose of Photoreceptors?

A

*Different types of cells contain different pigments
*Pigments are broken down by different wavelengths of light

41
Q

What is Circadian Photoreception?

A

Some cells in the retina are not involved with vision
* They contain a protein called melanopsin
* Signals from these cells don’t go to the visual cortex but to the circadian clock
region of the brain (suprachiasmatic nucleus)
* The suprachiasmatic nucleus influences the pineal gland to release melatonin
- Input from the melanopsin cells signals daylight →no release of melatonin
*BTW, melanopsin is most sensitive to blue light
- Why it is not a good idea to look at your phone or computer screen late at night

42
Q

What is the Visual Pathway?

A

*Optic nerve →optic chiasma →optic tract→thalamus →optic radiations→occipital lobe (primary visual cortex)

43
Q

What is the optic disc?

A

Optic disc
* Location at back of eye where axons of ganglion cells leave eye
* Called blind spot
* No photoreceptors

44
Q

what is the internal structure of the eye?

A

*Fovea centralis is located in the center of the macula lutea
- Only cones
- Greatest visual acuity here
- Why central vision is sharpest
*Age-related macular degeneration (AMD)
- Progressive deterioration of macula lutea portion of the retina

45
Q

What are the fovea centralis and macula lutea?

A

*The fovea centralis is in the middle of the macula lutea
*The goal is for light that enters the eye to land on the fovea centralis
- There are only cones here
- Greatest visual acuity
*If the focal point does not land on the
fovea centralis, then the image is
blurry

46
Q

What is the lens of the eye?

A

*Simple cuboidal epithelium along anterior surface
*Concentric layers of fibers produced by epithelial cells
*Ciliary body changes shape to focus light on fovea centralis
*Separates anterior segment from posterior segment of eye
- Anterior segment contains aqueous humor
- Posterior segment contains vitreous humor

47
Q

What is the anterior segment?

A

Anterior segment
*Anterior 1/3 of eye (cornea to lens)
*Has two chambers:
- Anterior chamber
– Anterior to iris
- Posterior chamber
– Between iris and lens

48
Q

What is the Aqueous Humor?

A

Anterior segment is filled with aqueous humor
*A blood filtrate from ciliary bodies
*Supplies nutrients and oxygen to lens and cornea
*Removed by scleral venous sinus

49
Q

Process of the aqueous humor?

A

Ciliary processes of ciliary body
1. Produces aqueous humor
2. Aqueous humor circulates through anterior segment of eye
3. Scleral venous sinus Removes aqueous humor

50
Q

What is Glaucoma?

A

*Condition where aqueous humor is drained slower than it is produced
*Increases intraocular pressure
* Damages optic nerve
* Leading cause of irreversible blindness in the world

51
Q

What is the Posterior Segment?

A

*Poster 2/3 of eyeball
*Behind lens
*Contains vitreous humor
- 98% water
- Collagen (much more viscous than aqueous humor)
- Supports lens and retina
- Helps maintain shape of eyeball

52
Q

Emmetropic eye

A

Emmetropic eye
* Normal vision
* Light focuses on retina (fovea centralis)

53
Q

Myopic eye

A

Myopic eye
* Nearsighted (can see things up close, not far)
* Eye may be too long, image focuses in front of retina
* Correction: concave lens

54
Q

Hyperopic Eye

A

Hyperopic Eye
* Farsighted (can see things far away, not close)
* Eye may be too short, image focuses behind retina
* Correction: convex lens

55
Q

Presbyopia

A

Presbyopia
* Lens becomes less elastic with age—need bifocals

56
Q

What is lasik surgery?

A

*Surface of cornea is reshaped using a laser
*This functions to re-direct light properly onto retinal surface

57
Q

What is Astigmatism?

A

*Abnormal shape of corneal surface causes light rays to diffract differently
*Result: two or more focal points

58
Q

What is a Detached Retina?

A

*A hole or small tear in the retina allows vitreous humor to leak between the pigmented and neural layers of retina
*Photoreceptor cells will eventually die if neural layer is not reattached to the nourishing underlying layer

59
Q

What is a Cataract?

A

Lens becomes cloudy
* Most commonly due to age-related damage to the internal part of lens
* Excessive sunlight, smoking, oral steroids can contribute
* Treatment: lens replacement

60
Q

What is the Snellen Eye Chart?

A

*For accurate results chart must be of correct size and individual must stand 20 feet away and read smallest line they can
*20/20 vision: individual can read from 20 feet what the “normal” eye can
*20/50 vision: individual can read from 20 feet what the normal eye could read from 50 feet

61
Q

What is the ear?

A

*Sensory functions:
- Hearing
- Balance and equilibrium
*Divided into 3 regions:
- External ear
+ Collects and directs sound waves
- Middle ear
+ Amplifies and transmits sound waves
* Internal (inner) ear
+ Location for sensory organs for hearing and equilibrium

62
Q

What are the External Ear Structures?

A

*From auricle up to tympanic membrane
(= eardrum)
*Auricle (pinna)
*External acoustic meatus

63
Q

What is the Auricle?

A

*Auricle (pinna)
- Outer fleshy portion; provides protection
- Made of elastic cartilage
– Ridges and cavities help the brain to locate where sounds are coming from
- Earlobe = lobule (no cartilage)

64
Q

What is the External acoustic meatus?

A

External acoustic meatus
* Air-filled canal
* Stratified squamous epithelium lines canal
* Hairs keep insects and foreign material out
* Ceruminous glands and sebaceous glands
- Secrete cerumen (wax) which inhibits microorganism growth, traps dust, repels insects

65
Q

What is the Middle Ear?

A

*The middle ear extends from the tympanic membrane to oval window
*Contains the auditory ossicles
- Malleus
– Attached to tympanic membrane
- Incus
- Stapes
– Attached to oval window

66
Q

What is the Pharyngotympanic tube?

A

*Pharyngotympanic tube (eustachian tube) connects middle ear with pharynx
- This allows for throat infections to move to the middle ear (= otitis media)
- A myringotomy may be needed to drain excess pus

67
Q

What are the ossicles?

A

*The ossicles amplify the pressure from the sound vibrations 20-fold at the oval window
*Two skeletal muscles help dampen sound
- Tensor tympani attaches to malleus
- Stapedius attaches to stapes

68
Q

What is the internal ear made of?

A
  1. The bony labyrinth
  2. The membranous labyrinth
69
Q

What is the bony labyrinth?

A

The bony labyrinth
* Cavity in the petrous portion of temporal bone
* Parts are:
- Semicircular canals
- Vestibule
- Cochlea

70
Q

What is the membranous labyrinth?

A

The membranous labyrinth
* Continuous series of membrane-walled sacs and ducts that fit loosely within bony labyrinth
* The membrane is thin layer CT lined with simple squamous epithelium
- Some thickened regions contain receptors for equilibrium and hearing
Components of membranous labyrinth
* Semicircular ducts (in semicircular canals)
* Utricle and saccule (in vestibule)
* Cochlear duct (scala media) (in cochlea)

71
Q

What is the Endolymph and Perilymph?

A
  • The membranous labyrinth structures are filled with clear liquid = endolymph
  • Outside membranous labyrinth is perilymph that is continuous with CSF in subarachnoid space
    – Perilymph and endolymph do not meet
72
Q

What is Cochlea and Cochlear Duct?

A

*The cochlea is a very small (size of a split pea), spiraling chamber
- The coiling is around a central pillar of bone = modiolus
- The cochlear nerve is located in the modiolus
*The cochlear duct (scala media) is within the cochlea
*Cochlear duct has sensory receptors for hearing

73
Q

What are the components of Cochlear Duct?

A

*Cochlear duct (also called scala media) is filled with endolymph
- This duct is between two perilymph-filled chambers: scala vestibule and scala tympani
*The base of the cochlear duct sits on the basilar membrane

74
Q

What is the Spiral Organ?

A

*The spiral organ (= organ of Corti), inside the cochlear duct, has
- One row of inner hair cells and
- Three rows of outer hair cells
*Stereocilia at the tips of hair cells are embedded in tectorial membrane
*At base of hair cells are the fibers of the cochlear nerve
-These bipolar neuron cell bodies are in the spiral ganglion in the modiolus

75
Q

What is the Role of Cochlea in Hearing?

A

*Sound waves vibrate tympanic membrane
*Ossicles vibrate, pressure is amplified
*Stapes pushes on oval window
* Perilymph in scalavestibuli moves/vibrates
* Sound waves in hearing range go through cochlear duct
- Basilar membrane vibrates
- Tectorial membrane does not move
- Stereocilia on inner hair cells are bent
* Action potentials stimulate cochlear nerve

76
Q

High Pitch versus Low Pitch Sounds

A

*The frequency (pitch) of the sound waves will cause deflection of the basilar membrane at different places
- Low pitch (low frequency) sounds deflect deep into cochlea
- High pitch (high frequency) sounds deflect near entrance of cochlea

77
Q

What is the Inner versus Outer Hair Cells?

A

*Both are located in spiral organ
*Inner hair cells
- True receptors, transmit vibrations of basilar membrane to cochlear nerve
*Outer hair cells
- Tune and amplify signal (100X)
– Helps us hear faint signals
- Can produce otoacoustic emissions
– Sounds from ear
– Used to test hearing in newborns

78
Q

What is Utricle and Saccule?

A
  • Are membranous structures found within a bony vestibule
  • Both contain a macula
  • Region of sensory epithelium
  • Utricle
  • Responds to acceleration in a horizontal direction
    – Forward acceleration and deceleration
    – And head tilt (“yes”)
  • Saccule
  • Responds to verticalmovements
    – Up and down in an elevator
79
Q

What is Maculae?

A

Structures of maculae:
* Hair cells
* Supporting cells
* Otolith membrane
* Otoliths

80
Q

components of hair cells of maculae?

A

Hair cells
* Mechanoreceptor cells that respond to movement
* Stereocilia
– Extensions of hair cells that areembedded in otolithic membrane; initiate an impulse when bent

81
Q

Components of supporting cells of the maculae?

A

Supporting cells
* Simple columnar epithelium that
provides protection & support

82
Q

Components of Otolith membrane of the maculae?

A

Otolith membrane
* Jelly like disc that sits atop sensory epithelium & shifts in response to movement (bend stereocilia)

83
Q

Components of Otoliths membrane of the maculae?

A

Otoliths
* Calcium carbonate crystals that add weight to membrane and cause more dramatic shift

84
Q

What are the Semicircular Canals and Ducts?

A

*The membranous semicircular ducts are within the bony semicircular canals
*Are involved with rotational acceleration of the
head
*Each duct has a swelling = membranous ampulla

85
Q

What are crista ampullaris?

A

*Inside each membranous ampulla is a crista ampullaris
- Contain receptor cells that measure rotational acceleration

86
Q

What are the structures of the crista ampullaris?

A

Structures of crista ampullaris:
* Supporting cells: simple columnar epithelium; support & protect hair cells
* Hair cells: mechanoreceptors; respond to rotational forces
* Stereocilia: extensions of hair cells that are embedded in ampullary cupula; initiate an impulse when bent
* Ampullary cupula: gelatinous mass that “tips” under rotational forces , bending the stereocilia