Digestive System Flashcards
What is the primary function of digestive system?
Primary Function of Digestive System
* To break down food and/or liquids into smaller units of absorbable nutrients which are used by your body to generate energy
On average how
long do you think it takes for the sandwich you ate at lunch to
completely pass through your digestive tract?
24 hours
What is the Alimentary canal?
Alimentary canal
* Structures form long tube that breaks down food
* It takes approximately 24 hours from ingestion to defecation
What are the Accessory digestive organs?
Accessory digestive organs
* Participate in digestive process but food does not pass through
these structures
* Examples:
- Liver
- Pancreas
- Gallbladder
- Salivary glands
What is Ingestion?
Ingestion
* Put food into mouth
What is Propulsion?
Propulsion
* Movement of food through canal
* Swallowing is voluntary
* Peristalsis is involuntary
What is Mechanical digestion
Mechanical digestion
* Physical breakdown of food particles
* Chewing, churning, segmentation
What is Peristalsis?
Peristalsis
* An organized contraction and relaxation of smooth muscle layers that propels food through the alimentary canal in one direction
- Ex. cookie dough gets squeezed out
- Allows you to eat upside down
What is Segmentation?
Segmentation
* Contractions of smooth muscle move chyme (food product being digested) back and forth within canal to allow mixing and further breakdown
- mix up food particles and digestive enzymes
- homogenous mixture of food and enzymes
What is Chemical digestion?
Chemical digestion
* Enzymes and chemicals break down food
What is Absorption?
Absorption
* Particles (ex. Sugars, fatty acids, etc.) are
transported from canal into blood and lymph
capillaries
What is Defecation?
Defecation
* Indigestible products are eliminated as feces
What are the layers of the Alimentary Canal
- The inner canal = lumen
- There is a consistent layering of tissues that form most of
the alimentary canal (there are some exceptions to be noted later) - From lumen to outer layer:
- Mucosa: lines lumen
- Submucosa: support layer
- Muscularis externa: muscle layer
- Serosa: outer surface
What are the 3 sublayers of Mucosa?
3 sublayers:
1. Epithelium
* Type varies by location
* Mucus production, absorption, protection, etc.
* Continuous & contains many digestive glands
2. Lamina propria (loose areolar)
* Capillary rich (absorption)
* MALT = mucosa associated lymphoid tissue
* Provides defense
3. Muscularis mucosa (thin layer smooth
muscle)
* Localized movements, helps glands expel
contents
What are the components of submucosa?
Submucosa
* Similar to loose areolar CT but more collagen fibers (provide support)
* Highly vascularized
- Nutrient absorption
* Glands connecting to lumen may project to submucosa
* Submucosal nerve plexus
- Control of muscle cells, glandular secretions, etc. (more on this later…)
What are the components of Muscularis Externa?
Muscularis Externa
* 2 layers smooth muscle (stomach has 3)
* Circular: inner layer, typically squeezes tube
* Longitudinal: outer layer, typically shortens tube
* Peristalsis and segmentation
* Myenteric nerve plexus
* Innervates muscularis externa and is between longitudinal and circular muscles (more on this later…)
What is the enteric nervous system?
- The enteric nervous system controls smooth muscle and
glands of alimentary canal - Considered the “brain in the gut” - - Has as many neurons as the entire spinal cord
- Reflex arc exists (sensory neurons –> interneurons –> motor neurons)
- Made of two nerve plexuses within the wall of alimentary canal
- Submucosal nerve plexus
- Myenteric nerve plexus
- Is influenced by the autonomic nervous system
What are the components of Serosa?
Serosa
* Found around organs within abdominal cavity
* Simple squamous epithelium + a thin loose areolar CT = Serous membrane
What is esophagus lined with?
- The esophagus is lined with adventitia (a fibrous CT)
- The esophagus is not contained
within a body cavity lined with a
serous membrane
What is Enteric Nervous System?
Enteric Nervous System
* Is located entirely within the wall of the alimentary canal
* Nerve plexuses allow for a localized response within visceral organs
* Partly independent of central nervous system
* Myenteric nerve plexus
* Submucosal nerve plexus
What is the Myenteric nerve plexus?
Myenteric nerve plexus
* Controls peristalsis and segmentation
* Within muscularis externa
What is the Submucosal nerve plexus?
Submucosal nerve plexus
* Controls secretions of glands & muscularis mucosa contractions
* Within submucosa
What is the Submucosal nerve plexus?
Submucosal nerve plexus
* Controls secretions of glands & muscularis mucosa contractions
* Within submucosa
What is the oral cavity?
Oral Cavity
* Mouth
* Ingestion of food
* Mechanical digestion
- Chewing = mastication
* Chemical digestion
- Mixed with saliva that contains amylase
– Starts chemical breakdown of carbohydrates
What is the Anatomy of the Mouth?
Mouth Anatomy
* Stratified squamous epithelium
* Thin submucosa layer anchored directly to underlying bone
* No muscularis externa or serosa/adventitia
* Lips
What is the Anatomy of the Lips?
Lips: margin between skin and oral cavity (lip proper = transition part)
* Poorly keratinized, translucent
- Red color from underlying capillaries
* No eccrine or sebaceous glands
* Lower lip 12X more likely to get nonmelanoma skin cancer
What is the Anatomy of the tongue?
Tongue
* Accessory digestive organ
* Superior surface (the part you see when you say “ah”) iscovered in keratinized stratified squamous epithelium
- Keratin makes it look whitish
* Moves food, helps mix to form bolus
(also involved with speech)
* Filiform papillae
- Rough surface
* Fungiform and circumvallate papillae
- Contain taste buds
What is the Lingual Frenulum?
Lingual Frenulum
* Lingual frenulum
* Fold of mucosa layer
* Connects tongue to floor of mouth
What is being “Tongue Tied”
Tongue Tie”
* If lingual frenulum extends too far forward, the tip of the tongue cannot move and speech is difficult
* Called ankyloglossia
* Makes saying sounds where the tongue touches teeth (letters such as t, z, p)
* Can be corrected surgically
What are the components salivary glands?
Salivary Glands
* Accessory digestive organs
* Exocrine glands
* Produce saliva
What are the components of salvia?
Saliva
* Moistens mouth
* Dissolves food (so can taste)
* Contains digestive enzymes
- Amylase starts breakdown of carbohydrates
- Lipase begins digestion of fats
* Contains mucus (helps swallowing)
* Neutralizes acids produced by bacteria that promote decay (has bicarbonate buffer)
* Antibacterial and antiviral components
What are the cell types of the Salivary Glands?
Cell types
* Serous cells secrete digestive enzymes
* Mucous cells secret mucus
What are the primary salivary glands?
- Parotid gland and duct
- Submandibular gland and duct
- Sublingual gland and ducts
What are the components of Parotid glands and ducts?
Parotid gland and duct
* Largest salivary gland
* Contains serous cells
- Produce watery enzyme-rich secretion
* Empties near 2nd upper molar
What is Mumps?
Mumps
* Viral infection
- Parotid glands swell; painful
What are the components of Submandibular gland and ducts?
Submandibular gland and duct
* Approximately equal amounts of serous and mucous cells
* Ducts open lateral to lingual frenulum
What are the components of Sublingual gland and ducts?
Sublingual gland and ducts
* Mostly mucous cells (secrete
mucus)
* Several ducts empty below
tongue
What are the components of teeth?
Teeth
* Accessory digestive organs
* Involved in mastication (= chewing)
* Heterodont dentition
* Different shapes of teeth for different jobs
What are Deciduous teeth?
Deciduous teeth
* “Baby teeth”
* 20 total erupt typically between ages 6 months
to 6 years
What are Permanent teeth?
Permanent teeth
* 32 total that gradually replace deciduous
* “Wisdom teeth” = 3rd molars
* Emerge between 17 and 25 years old (not always
can become impacted and do not emerge, or are
sometimes missing)
What are the regions of a tooth?
Regions of a Tooth
* Crown
- Part above gum line
* Neck
- Narrow, contained within gum tissue
* Root
- Contained within bone
What is the anatomy of teeth?
- Pulp
- Dentin
- Enamel
- Cement
- Periodontal ligament
What is the pulp of a tooth?
Pulp
* Loose areolar CT with blood vessels and
nerves
* Provides nutrients and sensation to tooth
* Odontoblasts create dentin
What is the Dentin of a tooth?
Dentin
* Collagen (from odontoblasts) and
minerals
* Forms bulk of tooth; deep to enamel
* Has radial striations = dentinal tubules
* Can contribute to tooth sensitivity
* No cells or blood vessels
* Harder than bone
What is the Enamel of a tooth?
Enamel
* Hardest substance in body
* 99% calcium salts
(hydroxyapatite crystals)
* No cells or blood vessels
What is the cement of a tooth?
Cement
* Calcified CT that covers root
What is the Periodontal ligament of a tooth?
Periodontal ligament
* Dense CT that attaches cement
of tooth to bony socket
What is a cavity?
Demineralization of enamel and dentin
* Begins with dental plaque
* Biofilm of sugar, bacteria and other
debris on teeth
* Bacteria break down sugars and produce
acids
* Dissolve calcium salts of teeth
(demineralization of enamel)
* Bacteria also produce protein-digesting
enzymes that destroy organic component
of teeth
What is the Root Canal Procedure?
- A root canal may be required when the pulp within the canal
becomes infected - Pulp is drilled out
- Tooth is now “dead”
- Cavity is sterilized and filled
- Tooth is capped off to help strengthen it
What is the Pharynx?
- Pharynx connects oral cavity to
esophagus and nasal cavity - 2 parts
- Oropharynx
- Laryngopharynx
- Muscularis externa has skeletal
muscle for swallowing - *Nasopharynx
What is the Oropharynx?
Oropharynx
* Immediately behind oral cavity
* Made of stratified squamous epithelium
What is Laryngopharynx?
Laryngopharynx
* Inferior to oropharynx
* Made of stratified squamous epithelium
What is the Esophagus?
Esophagus
* Connects pharynx to stomach
* Stratified squamous epithelium
(nonkeratinized)
* Mucous glands in submucosa
and mucosa secrete mucus
- Lubricates bolus of food as passes
through
What is the Muscularis externa of the Esophagus?
Muscularis externa
* Upper 1/3: skeletal muscle
* Middle 1/3: mix of skeletal and smooth
* Lower 1/3: smooth muscle
What is Hiatal hernia?
Hiatal hernia
* Superior part of stomach pushes through esophageal hiatus following weakening of diaphragmatic muscle fibers
- Acidic stomach juices are regurgitated, eroding wall of esophagus (= GERD, gastroesophageal reflux disease)