Sosnowski Skin Wounds Flashcards
flat lesion w/ well-circumscribed change in skin color less than 1 cm
macule (freckle)
macule greater than 1 cm (birthmark)
patch
elevated solid skin lesion less than 1 cm (mole, acne)
papule
papule greater than 1 cm (psoriasis)
plaque
small fluid containing blister less than 1 cm (chickenpox)
vesicle
large fluid containing blister greater than 1 cm (bullous pemphigoid)
bulla
vesicle containing pus
pustule
transient smooth papule or plaque (hives)
wheal
flaking off of stratum corneum (eczema, psoriasis)
scale
dry exudate (impetigo)
crust
increase in thickness of stratum corneum
hyperkeratosis
retention of nuclei in stratum corneum
parakeratosis
increase in thickness of stratum granulosum
hypergranulosis
epidermal accumulation of edematous fluid in intercellular spaces
spongiosis
separation of epidermal cells
acantholysis
epidermal hyperplasia (increase in spinosum)
acanthosis
natural cleavage lines of skin that heal better
Langer’s lines
controls body temperature
hypothalamus and skin
main neurotransmitter that controls temperature
Ach
4 steps in wound healing:
hemostasis
inflammation
proliferation
remodeling
raised scar that spreads beyond site of initial injury
Keloid
fastest type of closure of a wound; surgical incisions and paper cuts; normal steps
primary closure
wound edges cannot be closed so body will heal from bottom up
secondary closure
deals with traumatic injuries or infected wounds; often a graft needs to be used
delayed primary closure
sunburn; loss of epidermis only (painful); keratinocytes damaged
superficial burn
damages both epidermis and dermis (painful)
partial thickness burn
deals with layers all the way down to bone and damages nerves (not painful)
full thickness burn
burn triage uses
rule of nines
bruise; does not blanch w/ pressure
contusion
small blood vessel hemorrhage into tissues; does not blanch with pressure
purpura
partial thickness skin injury only involving epidermis
abrasion
full thickness skin injury
avulsion
blunt force trauma involving tearing of skin and maybe deeper tissues
laceration
hemoglobin reabsorption steps
RBC’s break out of blood vessels b/c of trauma
hemoglobin has to be recycled
macrophages pick it up (heme component)
break it down to biliverdin (more stable) (green)
broken down again into bilirubin (yellow) then processed in liver
hemoglobin reabsorption happens also in what
contusions/bruises
bruise that looks red/purple
days old
bruise that looks green to yellow
week old
bruise that looks bronze
weeks old
macrophages that have internalized hemoglobin (hemosiderin)
siderophages
skin aging:
epidermis decreased
discoloration
thinner skin
less collagen
best thing to use in anti-aging products
vitamin A (retinoid)
botulinum toxin blocks Ach release and is used for what
botox