Audia Skin and Muscle Infections II Flashcards

1
Q

caused by bacteria in the pores

A

skin abscesses

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2
Q

presence of inflammatory cells within the hair follicle

A

folliculitis

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3
Q

presence of pus and raised red surface

A

boil (furuncle)

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4
Q

cluster of boils(furuncles)

A

carbuncle

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5
Q

non-infectious folliculitis

A

acne

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6
Q

infectious folliculitis

A

furuncles and carbuncles

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7
Q

holocrine secretion of sebaceous glands

A

sebum

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8
Q

microbe that causes infectious folliculitis

A

Stap. aureus

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9
Q

first line of treatment for skin abscesses

A

clean and drain

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10
Q

to treat minor skin infections

A

topical bactroban (mupirocin)

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11
Q

to treat moderate skin infections

A

Clindamycin

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12
Q

to treat serious skin infections

A

Vancomycin

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13
Q

injury to knee DDx; erythema and edema

A

cellulitis or arthritis

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14
Q

inflammation of the dermis caused by infection; no necrosis

A

cellulitis

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15
Q

most common cause of cellulitis;( gram +, beta hemolytic, catalase - )

A

Group A Strep

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16
Q

if you see purple bullae involved in cellulitis, what 2 organisms are involved

A

Vibrio vulnificus
S. pneumoniae

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17
Q

to diagnose cellulitis

A

presentation

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18
Q

to treat mild cellulitis

A

Amoxicillin (penicillin b/c group A strep)

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19
Q

to treat penicillin sensitive cellulitis

A

Clindamycin

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20
Q

spreading infection of dermis that has facial rash that is itchy and tender

A

Erysipelas

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21
Q

microbe that causes Erysipelas

A

Group A Strep

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22
Q

caused by SPE superantigen and has rash like sandpaper and strawberry tongue

A

Scarlet Fever

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23
Q

sequellae group A strep

A

scarlet fever

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24
Q

caused by exfoliation toxin of S. aureus that cleaves desmoglein-1 (toxin disseminates)

A

Scalded Skin Syndrome

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25
Q

Connecticut resident
myalgia and arthralgia
erythematous bull’s eye skin lesion

A

Lyme Disease

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26
Q

this spirochete causes Lyme Disease

A

Borrelia burgdorferi

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27
Q

reservoir for lyme disease

A

mouse, deer

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28
Q

vector for lyme disease

A

deer tick

29
Q

primary stage of lyme disease

A

70% of patients with distinct rash

30
Q

secondary stage of lyme disease

A

knee complaints (contain spirochetes)

31
Q

tertiary stage of lyme disease

A

crippling arthritis; neurologic complications

32
Q

to diagnose lyme disease:

A

clinical presentation
serology for late stage

33
Q

to treat early lyme disease

A

doxycycline or amoxicillin

34
Q

to treat secondary and tertiary lyme disease stages

A

cephalosporins

35
Q

complication to Lyme disease where there is a cytokine storm and systemic response

A

Jarisch-Herxheimer Reaction

36
Q

NUMB rash, takes a very long time to develop symptoms after first exposure; armadillos

A

Leprosy

37
Q

stain used for Mycobacteria

A

Acid Fast stain

38
Q

causes chronic granulomatous disease of peripheral nerves and superficial tissues; skin lesions

A

Mycobacterium leprae

39
Q

milder form of leprosy

A

Tuberculoid

40
Q

more severe form of leprosy and is most infectious

A

Lepromatous

41
Q

most common in CA, LA, and Texas; armadillos transmit

A

Mycobacterium leprae

42
Q

obligate intracellular bacterial species that multiply very slowly and immunity to it is T cell mediated

A

M. leprae

43
Q

strong intracellular reaction, relatively few bacteria (less severe)

A

tuberculoid leprosy

44
Q

strong Ab response; but defect in specific cellular response (pathogen able to multiply—> more severe)

A

lepromatous leprosy

45
Q
A

tuberculoid on left and lepromatous on the right

46
Q

To diagnose M. leprae:

A

acid fast stain
skin reactivity test
PCR

47
Q

To treat Leprosy: tuberculoid form

A

rifampicin + dapsone

48
Q

to treat Leprosy: lepromatous form

A

rifampicin + dapsone + clofazimine

49
Q

complications from using vasopressors for a while

A

gangrene on extremities

50
Q

starts with minimal trauma (micro-abrasion) and organism spreads through subcutaneous tissue and deep fascia; extremely painful; can start as cellulitis

A

Necrotizing Fasciitis

51
Q

this can develop from necrotizing fasciitis and is death of muscle tissue

A

myonecrosis

52
Q

Necrotizing Fasciitis vs. Gas Gangrene

A

NF starts w/ minimal trauma

53
Q

organism that most often causes necrotizing fasciitis

A

Group A Strep

54
Q

Group A Strep produces what 3 things that help illicit NF

A

superantigen
streptodornase
streptokinase

55
Q

a score of >6 on LRINEC means what

A

NF

56
Q

type I NF

A

polymicrobial

57
Q

microbes that make up type I NF

A

stap, strep, enterococci

58
Q

Type II NF

A

monomicrobial

59
Q

microbe that makes up type II NF

A

Group A Strep

60
Q

marine injuries are associated with what microbe that can cause NF

A

Vibrio vulnificus

61
Q

bacterial virulence factors for NF

A

exotoxins, endotoxins(LPS), and superantigens

62
Q

predisposing factor to NF

A

diabetes

63
Q

To treat NF:

A

Vancomycin + piperacillin/tazobactam

64
Q

CC: lumpy jaw and suppuration/tenderness

A

Actinomycosis

65
Q

gram + rod, filamentous, NOT acid fast

A

Actinomyces

66
Q

infection by this anaerobic microbe is by minor dental trauma and endogenous source; slowly developing infections

A

Actinomyces

67
Q

forms “molar tooth” colonies on blood agar

A

Actinomyces

68
Q

colonies of this infection are sulfur granules and appear yellow/orange; cervicofacial infections and draining sinus tracts

A

Actinomyces

69
Q

To Treat Actinomycosis

A

Penicillin G