Sos Digestive ILA Flashcards
laryngeal SCC risk factors
smoking
alcohol
intestinal metaplasia- Barrett’s esophagus
____-grade dysplasia
high
Barrett’s esophagus
steps from barrett’s to adenocarcinoma
intestinal metaplasia to dysplasia to esophageal adenocarcinoma
esophagus
invasive adenocarcinoma
most common cancer of esophagus in the US (white men)
adenocarcinoma
most common cancer of esophagus worldwide
SCC
where does esophageal SCC most commonly occur
upper and middle esophagus
L to R
normal, metaplasia, invasive cancer
keratin pearls (SCC)
dystrophic calcification
porcelain gallbladder
rare
female predominance
60-70 yrs
gallbladder adenocarcinoma
metastatic liver cancer
often found in a cirrhotic liver
hepatocellular carcinoma
risk factors: H pylori and smoked foods
intestinal type stomach adenocarcinoma
not associated with H pylori or smoked foods
diffuse type, signet ring cell stomach cancer
in the colon
60-70 yrs of age
colorectal carcinoma
most common type of colorectal carcinoma arises from what
dysplasia
mutation sin DNA mismatch repair enzymes (MLH-1, MSH-2)
Lynch syndrome (leading to colorectal carcinoma)
aka hereditary nonpolyposis colorectal carcinoma
normal epithelium to dysplastic epithelium with what gene mutation
APC
dysplasia to adenoma gene mutation
KRAS
adenoma to carcinoma gene mutation
P53
