Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Year 2 Psychiatry > Somatic therapies I > Flashcards

Somatic therapies I Flashcards

1
Q

mood stabilizing drugs act on what level? on what time scale? why?

A
  • cellular level
  • long term
  • change transcription
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

imipramine is used primarily for __________

A

nocturnal enuresis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

which SSRIs have active metabolites?

A
  • fluoxetine

- sertraline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what can be used to manage the tremor side effect of SSRIs?

A

propanolol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what are the early symptoms of serotonin syndrome? late?

A

EARLY:

  • lethargy
  • restlessness
  • mental confusion
  • flushing
  • diaphoresis
  • tremor

LATE:

  • hyperthermia
  • hypertonicity
  • rhabdomyolysis
  • renal failure
  • death
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

have SSRIs been associated with increased suicides?

A

NO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is the MOA of buproprion?

A

inhibits reuptake of DA and NE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is the main risk / side effect of buproprion at high doses?

A

seizure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is the approved use of vilazodone? what is the MOA?

A
  • MDD

- SSRI and 5HT1 receptor partial agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is the approved use of trazodone? what is the MOA?

A
  • sleep agent

- weak inhibitor or serotonin but also blocks 5HT2 receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is the approved use of nefazodone? what is the MOA? what is the benefit?

A
  • MDD
  • weak inhibition of neuronal serotonin reuptake
  • no sexual dysfunction
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is the approved use of mirtazapine? what is the MOA?

A
  • MDD, sleep aid

- potent antagonist at postsynaptic 5HT2 and 5HT3 and central a1 adrenergic receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what drug class is clomipramine? what is the MOA? what is the approved use?

A
  • TCA
  • OCD
  • SSRI
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what are the side effects of TCAs?

A
  • antihistamin: sedation, weight gain

- anticholinergic: constipation, urinary retention, dry mouth, vision blurring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

which drug class is better at achieving remission?

A

dual acting agents like SNRIs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what are the goals for antidepressant medications?

A
  • diagnose early
  • treat remission
  • maximize functionality
17
Q

what is the timeframe for SSRIs to reach maximum benefit? if no response, what do you do?

A
  • 2-3 months

- increase every 3-4 weeks until max dose is reached

18
Q

what are augmentation strategies?

A
  • add a second (different) antidepressant class
  • lifestyle changes
  • sleep promoters
  • psychotherapy
  • buspirone
  • stimulants
19
Q

what antidepressant has the least risk to the fetus in pregnant / nursing mothers? what is the best strategy for nursing mothers?

A
  • SSRIs (sertraline)

- nursing mothers: sertraline

Year 2 Psychiatry (28 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions