Solvents Flashcards
0
Q
chronic effect?
A
damage to NS, heart, kidney, liver, lung
1
Q
Acute effect?
A
narcotic
2
Q
Most toxic aliphatic hydrocarbon?
A
n-hexane (neurotox.)
3
Q
Chronic effect of benzene? (C6H6)
A
carcinogenic, immunotoxic! (lowers B & C cell count.)
4
Q
Effect of Toluene?
A
narcotic
5
Q
what is in nail polish remover?
A
ethyl acetate
6
Q
what are solvents used for?
A
dilution, solvation of matter w/out chem. rxn.
7
Q
metabolism of EtOH?
A
EtOH –> (ADH) Acetaldehyde –> (ALDH) Acetate
8
Q
how to induce EtOH intolerance? why?
A
Disulfiram, inhibition of ALDH.
9
Q
how to treat MeOH intox., why?
A
inhibition of prod. of formic acid
10
Q
ethylene glycol particularly toxic for…?
A
kidney
11
Q
why does the toxicity of benzene and toluene differ?
A
chem. properties: benzene oxidized at aromatic ring, toluene not.
