Natural Compounds

Question 0

effect morphine? class?

Answer 0

isochinolin alkaloids, reduces pain, boosts mood, pot. addictive (mental & physical)
up to 20% in Opium.

Question 1

Examples Tropan Alkaloids?

Answer 1

Atropin (blocks act. of AcCh receptor)
Cocain
Scopolamin (AcCh rec)

Question 2

Indol alkaloids?

Answer 2

Strychnin (claviceps?)

LSD

Question 3

effect furanocumarine?

Answer 3

phototoxicity

Question 4

effect cardiac glycosides?

Answer 4

exchange Na and K at channels! (K out, Na in)

Question 5

Deathcap affects which organ`?

Answer 5

liver => failure

Question 6

coprin (inkcap) effect?

Answer 6

inhib ALDH => no metabol. of alcohol, rise in acetaldehyde levels.

Question 7

aflatoxin affects which organ?

Answer 7

liver (failure if high conc., if chronic => liver cancer!)

Question 8

ochratoxin organ?

Answer 8

kidney (carcinogenic)

Question 9

bacterial toxins? (2 classes)

Answer 9

• cell wall compounds: endotoxins (LPS)

- Exotoxins: choleratox., botulinumtox., tetanustox.

Question 10

animal toxins work where?

Answer 10

often neuromuscular endplate