Polyhalogenated Hydrocarbons Flashcards
acute tox. of chlorinated aliphatic hydrocarbons?
CNS depression
chlorinated aliphatic hydrocarbons derived from?
methane, ethane, ethene
what does the C-Cl bond do in chlorinated aliphatic hydrocarbons?
gives lipophilicity, protects comp. from ox. metabolism, reduces reactivity
What do halogenated aliphatic hydrocarbons do?
destroy ozone
halogenated aliphatic hydrocarbons persistent?
yes
halogenated aliphatic hydrocarbons used for?
freezing agents, propellants
halogenated dioxines & furanes persistent?
yes, POP
halogen dioxines & furanes accumulate in food chain ?
yes, in fat tissue, because very lipophil.
most active halogenated dioxines & furanes?
TCDD
effect TCDD?
binds Ah-receptor
halogenated biphenyls effect?
block Ah-receptor, but less potent
PCB?
PBB?
Polychlorinated biphenyl
Polybrominated biphenyl
halogenated biphenyls effect on human?
might reduce cognition
some mutagenic
tumor promoting
