Soil borne Funal Flashcards
CA - Histoplasmosis
Histoplasma capsulatum
VF - histoplasmosis
- dimorphic fungus, fungal mold spores
- yeast-form grows intracellulary in macrophages
Reservoirs - histoplasmosis
1- bird & bat droppings
2- soil
Airborne Conidia
(Histoplasmosis)
By inhalation of microscopic fungal spores
Sxs - histoplasmosis
- forms lung lesions
- fungemia (systemic infection)
- mostly asymptomatic
- flu-like mild sxs resembling tuberculosis
Diagnosis - histoplasmosis
Culturing of lung tissue or sputum sample; chest x-ray
Who is at high risk for histoplasmosis?
Chicken, bird handlers AND cave explorers
Pre-disposing factors - histoplasmosis
Commonly occurs in the Mississippi and Ohio river valleys
Prevention - histoplasmosis
No vaccine
Treatment - histoplasmosis
Anti fungals/ antimycotics
Coccidioidomycosis AKA
Valley fever OR San Joaquin fever
CA - coccidioidomycosis
Coccidioides immitis
VF - Coccidioidomycosis
- dimorphic fungus, fungal spores
- complex lifecycle of C. Immitis
Transmission - coccidioidomycosis
By inhalation of fungal spores called airborne arthroconidia —> spherules in tissue —> release endospores
Sxs - valley fever
- mostly asymptomatic
- flu like mild sxs resembling tuberculosis