Small Intestine Structure and Function Flashcards

1
Q

What does the small intestine consist of ?

A

The duodenum, the jejunum and the ileum

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2
Q

What occurs in the duodenum/jejunum and the ileum ?

A

Duodenum: Gastric acid neutralisation; Digestion;Iron absorption.
Jejunum: Nutrient absorption
Ileum: NaCl/H2O absorption and chyme dehydration

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3
Q

What enhances the absorptive ability of the small intestine ?

A

By folds, villi and microvilli increasing the surface area.

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4
Q

What occurs within the crypts of the small intestine ?

A

Secrete water

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5
Q

How much water is secreted by the small intestine daily ?

A

1500ml

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6
Q

What is present on the brush border that allows the passage of Cl ions ?

A

CFTR channels

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7
Q

What are the 2 types of movement in intestinal mobility ?

A

Segmentation

Peristalsis

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8
Q

What is the most common form of intestinal motility during a meal and what does this invlolve ?

A

Segmentation

Contraction and relaxation of short intestinal segments

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9
Q

Following the absorption of nutrients ___ stops and ____begins.

A

Segmentation

Peristalsis

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10
Q

What is MMC ?

A

Migrating Motility Complex (MMC)

Pattern of peristaltic activity travelling down the small intestine from the antrum.

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11
Q

MMC acts to…

A

1: Move digested material into the large intestine
2: Limit bacterial colonisation of the small intestine

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12
Q

What hormone is involved in the initiation of MMC ?

A

Motilin

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13
Q

Explain the law of the intestine

A

If the intestinal muscle is distended:
The muscle on the oral side of the bolus contracts
The Muscle on the anal side of the bolus relaxes
Bolus is then moved towards the area of relaxation, i.e. towards the colon.

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14
Q

What is the ‘law of the intestine’ mediated by and where is this found ?

A

Mediated by neurons in the myenteric plexus which is found between the layers of the muscularis

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15
Q

Explain the gastroileal reflex

A

Gastric emptying causes increased activity in the ileum which pushes the chyme into the colon

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16
Q

How are the contractions within the small intestine generated ?

A

By pacemaker cells within the longitudinal muscle layer (BER) this basic electrical rhythm produces oscillations in the membrane potential.

17
Q

What determines the strength of the contractions within the small intestine ?

A

The frequency of the action potentials

18
Q

What determines the frequency of segmentation ?

A

BER

19
Q

What increases/decreases contractions ?

A

Parasympathetic: Increases contractions
Sympathetic: Decreases contractions