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Systems: The Alimentary System > Liver Symposium > Flashcards

Liver Symposium Flashcards

1
Q

Which forms of Hepatitis are enteric viruses ?

A

A & E

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2
Q

Which forms of Hepatitis are Parenteral viruses ?

A

B,C and D

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3
Q

Which forms of Hepatitis cause self-limiting acute infections ?

A

A and E

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4
Q

Which forms of Hepatitis cause chronic disease ?

A

B,C and D

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5
Q

What are the high risk groups fro contraction of Hepatitis A ?

A 
Travellers
Patients with chronic liver disease
Haemophiliacs 
Occupational exposure 
Men who have sex with men
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6
Q

What is the structure of the Hepatitis B virus ?

A

It is much like an egg with and outer surface antigen and an inner protein core.

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7
Q

What aspect of the hepatitis B sits in the liver and cannot be detected in the blood ?

A

Hepatitis core antigen (HBcAg)

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8
Q

What aspect of Hepatitis B is detectable in the blood and proves presence of virus ?

A

Hepatitis surface antigen (HBsAg)

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9
Q

What shows that there is an active replicating hepatitis B virus within the host ?

A

Hepatitis e antigen (HBeAg)

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10
Q

Which antibody present within the body shows that you are protected against Hepatitis B ?

A

Anti-HBs

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11
Q

Which antibody present within the body shows that the patient has an acute Hepatitis B infection ?

A

IgM anti-HBc

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12
Q

Which antibody present within the body shows chronic infection/exposure to Hepatitis B ?

A

IgG anti HBc

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13
Q

Which antibody present within the body shows an inactive hepatitis B virus within the host ?

A

Anti-HBe

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14
Q

Does everyone with chronic Hepatitis B develop cirrhosis and ESLD ?

A

No

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15
Q

What are the 2 treatment options for those with a Hepatitis B viral infection ?

A

Pegylated interferon

Oral antiviral drugs

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16
Q

What is the presentation of an individual with a Hepatitis C infection ?

A

Most symptomatic until cirrhotic, many have normal LFT’s

17
Q

What type of virus is Hepatitis D ?

A

Small RNA virus

18
Q

What other virus is Hepatitis D associated with ?

A

Co-infection or super-infection with HBV

19
Q

NAFLD encompasses which 3 entities ?

A

Simple steatosis
Non alcoholic steatohepatitis
Fibrosis and cirrhosis

20
Q

With what other conditions is NAFLD associated with ?

A

Diabetes mellitus
Obesity
Hypertriglyceridemia
Hypertension

21
Q

What investigations should be carried out in order to diagnose NAFLD ?

A

Enhanced liver fibrosis panel (ELF)
Fibroscan
Biopsy
MR Spectroscopy: Actually quantify fat

22
Q

What is the recommended treatment for NAFLD ?

A 
Weight loss
Diet change
Exercise
Insulin sensitizers
Vit E
23
Q

Name 3 common autoimmune liver diseases

A

Autoimmune hepatitis
Primary biliary cholangitis (PBC)
Primary sclerosing cholangitis (PSC)

24
Q

What is found to be elevated in individuals with autoimmune hepatitis ?

A

IgG

25
Q

What are the 3 types of antibodies found in autoimmune hepatitis ?

A

Type 1: ANA, SMA
Type 2: LKM1
Type 3: SLA

26
Q

What kind of drugs does autoimmine hepatitis respond to well ?

A

Steroids

27
Q

What is found to be elevated in individuals with Primary biliary cholangitis?

A

IgM

28
Q

What part of the biliary system is often involved in Primary biliary cholangitis ?

A

Intrahepatic bile duct

29
Q

What are the 2 most common symptoms in Primary biliary cholangitis ?

A

Pruritis and Fatigue

30
Q

What parts of the biliary system are often involved in Primary sclerosing cholangitis ?

A

Intra and extrahepatic bile ducts involved

31
Q

What happens to the biliary system with Primary sclerosing cholangitis ?

A

Stricturing disease

32
Q

What is the test of choice to diagnose Primary sclerosing cholangitis ?

A

MRCP

33
Q

What are 2 main symptoms of Primary sclerosing cholangitis ?

A

Recurrent cholecystitis and jaundice

34
Q

Treatment options for Primary sclerosing cholangitis ?

A

Liver Tx and stenting

Systems: The Alimentary System (16 decks)

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