Sleep Apnoea And Narcoplesy Flashcards

1
Q

What is obstructive sleep apnoea syndrome?

A

Episodes of upper airway obstruction leading to apnoea during sleeping.

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2
Q

What are the characteristics of obstructive sleep apnoea?

A

Heavy snoring
Typically unrefreshing sleep
Daytime sleepiness
Poor daytime concentration

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3
Q

What factors contribute to a repeated closure of the upper airways?

A

Muscle relaxation
Narrow pharynx
Obesity

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4
Q

What does repeated closure of the upper airway lead to if the airways are fully closed?

A

Oxygen desaturation

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5
Q

What does repeated closure of the upper airway lead to if the airways arent fully closed?

A

Snoring

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6
Q

What is anapnoea?

A

When the airway is closed for 10 second or more

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7
Q

What is a hypopnea?

A

When it is nearly obstructed for 10 seconds or more

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8
Q

What is the consequence of apnoea and hypopneas?

A

The brain is working hard to move the person from deep sleep to light sleep.

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9
Q

What is a microarousel?

A

When the brain works hard to move the person from deep sleep to light sleep.

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10
Q

What are the consequence of frequent microarousels?

A

Poor concentration and daytime sleeping

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11
Q

Why are obstructive sleep apnoea syndrome important?

A

Impaired quality of life
Increased road traffic accidents
Also linked with hypertension, increased risk of stroke and heart disease.

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12
Q

What is the prevalence of sleep apnoea?

A

2% of adult men and 1% of adult women approx

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13
Q

How is obstructive sleep apnoea syndrome diagnosed?

A

History and examination
Epworth questionarre
Overnight sleep study (pulse oximetry, limited sleep studies and full polysomnography)

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14
Q

How is obstructive sleep apnoea graded?

A
Desaturation rate:
0-5 Normal
5-15 Mild
15-30 Moderate 
>30 Severe
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15
Q

How is obstructive sleep apnoea treated?

A

Identifying exacerbating factors (weight loss, alcohol reduction, diagnose and treat endocrine disorder)
Continuous positive airways pressure
Malibu are repositioning splint

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16
Q

What advise would you give sleep apnoea patients about driving?

A

Inform DVLA of their condition

They should be allowed to drive once their condition is treated.

17
Q

What are the main clinical features of narcolepsy?

A

Cataplexy (appearing to be sleeping, but they aren’t and aren’t really aware of their surrounding)
Daytime sleeping
Hallucinations
Sleep paralysis

18
Q

What is the treatment for Narcolepsy?

A

Modafinil
Dexamphetamine
Venlafaxine (for cataplexy)
Sodium oxybate (xylem)