Sleep Flashcards

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1
Q

Where is melatonin released from?

A

The pineal gland

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2
Q

what did michel siffre find out ?

A

that the circadian rhythm is 25 hours not 24

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3
Q

what part of the brain controls sleep?

A

the superchiasmatic nucleus in the anterior hypothalamus behind the optic chiasm. Has connections to the pineal gland which releases melatonin

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4
Q

how do melanopsin receptors work?

A

light presence sends signals to superchiasmatic nucleus which controls pineal gland and therefore melatonin release.

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5
Q

what is phase delay?

A

when the circadian rhythm is delayed and you wake up later

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6
Q

what is phase advance?

A

when the circadian rhythm is advanced and you wake up earlier.

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7
Q

what does the inactivity evolutionary sleep explanation hypothesise?

A

forces us to remain silent during hours where are more likely to get preyed on. thought to make animals adapt to their environmental niche. however being unconscious is not safe so this theory not proven

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8
Q

what does the energy conservation theory hypothesize?

A

sleep during dark hours when hunting and foraging would be less efficient. Basal temp (10% decrease) and caloric metabolism go down. however if this was true, sleep would not have such a major effect on other aspects of people

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9
Q

what is the recuperation/repair theory of sleep?

A

waste product removal and damage repair. If true then lack of sleep should cause physiological and psychological disturbances, deprivation should be able to get recovered with sleep debt and symptoms should get worse as time goes on.

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10
Q

How long did peter tripp and randy gardener stay awake for ?

A

tripp - 201 hours (8 days). showed psychosis at end
gardener - 264 hours (11 days). showed problems with concentration and STM, moodiness and did not recover debt in the following week

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11
Q

what is the glymphatic system?

A

when changes of vasodilation in the brain pump CSF around the brain. this interacts with interstitial (ec) fluid and picks up the waste products of metabolism to transport away. levels increase when sleep deprived.

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12
Q

what to EEG, EOG and EMG measure

A

EEG - overall electrical brain activity
EOG - eye movement (optic)
EMG - muslce activity (m for muscle)

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13
Q

what are the characteristics of the different stages of sleep?

A

awake - high freq beta waves
drowsy - alpha start
stage 1 and 2 - theta, spindles and mixed EEG activity
stage 3 and 4 - slow wave, more delta (slower)
REM - loss of muscle tone, low-voltage and high-frequency waves similar to being awake. 90% dreaming during REM

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14
Q

what does early/SWS sleep effect memory wise?

A

paired associate word list, declarative/explicit (somatic and episodic)

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15
Q

what does late/REM sleep improve memory wise?

A

mirror drawing, procedural/implicit memory

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16
Q

what was improved when presented during SWS compared to REM/conscious?

A

smell recollection, cueing memories

17
Q

does sleep increase or decrease problem solving and insight?

A

increase (Wagner et al, Nature) - sequqence word completion task

18
Q

what is hypnagogia?

A

involuntary spontaneous dream-like experiences that incorporate recent wake experiences. the transition between being awake and asleep

19
Q

what state of mind is non-rem stage 1 sleep associated with?

A

hypnagogia

20
Q

what are sharp-wave ripple events and when do they occur?

A

during SWS, a quick recollection of events occurs due to cells that were active in wake experiences being activated faster but still in the same order. this occurs in the hippocampus

21
Q

what are sleep spindles? and the difference between sharp-wave ripple events?

A

sleep spindles are associated with memory recall and the more dense the spindle is the more consolidated the memory will be. they occur with sharp wave ripples.

21
Q

what are sleep spindles? and the difference between sharp-wave ripple events?

A

sleep spindles are associated with memory recall

22
Q

how do the SWRs and sleep spindles help memory consolidation?

A

experience is encoded in the hippocampus and the representation of the experience is replayed at high speed which creates a SWR. the sleep spindles reflect how much the relayed experience engaged with the neocortex

23
Q

what did plihal and born study?

A

used a paired associate word list plus a mirror drawing task to test what parts of memory sleep affects