Sleep

Question 1

Tetrad of Narcolepsy type 1

Answer 1

• 3 months of sleepiness
• Cataplexy
• < 8 min mean sleep latency with 2 SOREMP
• <110 CSF hypocretin/orexin

Question 2

2 differences between tetrad of Type 2 narcolepsy as compared to type 1

Answer 2

No cataplexy

CSF hypocretin/orexin levels > 110

Question 3

4 drugs for narcolepsy daytime sleepiness

Answer 3

• Solriamfetol
  
  • Increases BP and HR
• Pitolisant
• Sodium oxybate
• Modafinil

Question 4

3 drugs for cateplexy in narcolepsy

Answer 4

• Sodium oxybate
• Pitolisant
• SSRI’s

Question 5

Treatment for idiopathic hypersomnia syndrome

Answer 5

Modafinil

(No FDA approved treatment, so this is off label)

Question 6

Definition of parasomnias

Answer 6

Physical or experiential phenomena that occur during sleep

Question 7

Parasomnia that has unpleasant dreams or dreams of being attack and large movements during REM sleep

Answer 7

REM sleep behavior disorder

Question 8

Main 2 treatments for parasomnias

Answer 8

Clonazepam

Melatonin (for RBD)