Skin Pathology - Bikman Flashcards

1
Q

erythema

A

redness

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2
Q

macule

A

flat lesion

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3
Q

papule

A

raised lesion

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4
Q

plaque

A

large papule

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5
Q

vescicle

A

blister

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6
Q

acantholysis

A

loss of intercellular cohesion in keratinocytes

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7
Q

acanthosis

A

diffuse epidermal hyperplasia

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8
Q

hyperkeratosis

A

thick stratum corneum

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9
Q

papillomatosis

A

surface elevation by hyperplasia

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10
Q

Impetigo

A

non-neoplastic; infectious
Cause: staph. aureus or strep. phyogene
Risk: children
Manifestation: pustules

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11
Q

Erysipelas

A

non-neoplastic; infectious
Cause: Strep
Risk: anyone
Manifestation: erythematous plaque

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12
Q

Necrotizing Fasciitis

A

non-neoplastic; infectious
Cause: many
Risk: kids
Manifestation: gangrene

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13
Q

Acne

A

non-neoplastic; infectious
Cause: propionibacterium acne
Risk: varies
Manifestation: blocked sebaceous glands

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14
Q

Ringworm

A

non-neoplastic; infectious
Cause: fungi
Risk: anyone
Manifestation: red, scaly, brown, athletes foot

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15
Q

Sporotrichosis (Gardner’s Disease)

A

non-neoplastic; infectious
Cause: fungi
Risk: anyone
Manifestation: painless papule

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16
Q

Verruca Vulgaris

A

non-neoplastic; infectious
Cause: HPV
Risk: any
Manifestation: cauliflower formation/blister

17
Q

Herpes Simplex

A

non-neoplastic; infectious
Cause: HSV
Risk: any
Manifestation: cold sores (HSV I) or genital herpes (HSV II)

18
Q

Erythema Multiforme

A

non-neoplastic; infectious
Cause: HSV or drugs
Risk: any
Manifestation: target lesions

19
Q

Molluscum Contagiosum (Water Warts)

A

non-neoplastic; infectious
Cause: poxvirus (MCV)
Risk: any
Manifestation: centrally umbillicated papules

20
Q

Scabes

A

non-neoplastic; infectious
Cause: sarcoptes scabei
Risk: any
Manifestation: rash on skin folds

21
Q

Urticana (Hives)

A

non-neoplastic; inflammatory
Cause: mast cell degranulation
Risk: any
Manifestation: erythemtous, edematous, pruntic

22
Q

Psoriasis

A

non-neoplastic; inflammatory
Cause: inherited, genetic
Risk: any
Manifestation: itchy red lesions

23
Q

Lichen Planus

A
non-neoplastic; inflammatory
Cause: immunity medication
Risk: any
Manifestation: purple polygonal papules
Wickham's strale
24
Q

Atopic Eczema

A

non-neoplastic; inflammatory
Cause: inherited, genetic
Risk: any
Manifestation: itchy rash

25
Q

Pemphigus Vulgaris

A

non-neoplastic; bullous
Cause: antibodies attack intercellular junctions
Risk: 40-50 years of age
Manifestation: superficial bullae, mouth then skin (Tzanck’s cells)

26
Q

Bullous Pemphigold

A

non-neoplastic; bullous
Cause: antibodies against basement membrane
Risk: elderly
Manifestation: big, subepidermal bullae of groin, axilla, arms and mouth

27
Q

Nevus (mole)

A

Neoplastic; Benign Tumor
Cause: benign proliferation of melanocytes
Manifestation: depends on location

28
Q

Hemanginoma

A

Neoplastic; Benign Tumor

common benign tumor of blood vessels

29
Q

Keratoacanthoma

A

Neoplastic; Benign Tumor
aberrant hair follicle
crater like nodule
can be a possible squamous cell carcinoma

30
Q

Seborrheic Keratosis

A

Neoplastic; Benign Tumor
benign epidermal tumor
flat, brown, velvety plaque
can be a sign of Leser-Trelat

31
Q

Actinic Keratosis

A

Neoplastic; Benign Tumor
benign neoplasm of epidermis
rough spots with erythematous base on sun-exposed skin
malignant if untreated

32
Q

Basal Cell Carcinoma

A

Neoplastic;

malignant tumor of basal layer

33
Q

Squamous Cell Carcinoma

A

Neoplastic; malignant

tumor of squamous epithelium

34
Q

Kaposi Sarcoma

A

Neoplastic; vascular
malignant tumor of lymphatic epithelium that intersects blood vessels
would get red bumps
AIDS patients and Ashkenazy Jews have higher incidence

35
Q

Angiosarcoma

A

Neoplastic; vascular
malignant tumor of endothelial type
bruise-like patterns progressing to lesions

36
Q

Peutz-Jeghers Syndrome

A

Neoplastic; vascular
genetic mutation
GI polyps and mucosal hyperpigmentation
can lead to many malignancies