Skin Pathology - Bikman Flashcards by Stephanie Sue

erythema

redness

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macule

flat lesion

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papule

raised lesion

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plaque

large papule

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vescicle

blister

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acantholysis

loss of intercellular cohesion in keratinocytes

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acanthosis

diffuse epidermal hyperplasia

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hyperkeratosis

thick stratum corneum

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papillomatosis

surface elevation by hyperplasia

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Impetigo

non-neoplastic; infectious
Cause: staph. aureus or strep. phyogene
Risk: children
Manifestation: pustules

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Erysipelas

non-neoplastic; infectious
Cause: Strep
Risk: anyone
Manifestation: erythematous plaque

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Necrotizing Fasciitis

non-neoplastic; infectious
Cause: many
Risk: kids
Manifestation: gangrene

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Acne

non-neoplastic; infectious
Cause: propionibacterium acne
Risk: varies
Manifestation: blocked sebaceous glands

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Ringworm

non-neoplastic; infectious
Cause: fungi
Risk: anyone
Manifestation: red, scaly, brown, athletes foot

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Sporotrichosis (Gardner’s Disease)

non-neoplastic; infectious
Cause: fungi
Risk: anyone
Manifestation: painless papule

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Verruca Vulgaris

non-neoplastic; infectious
Cause: HPV
Risk: any
Manifestation: cauliflower formation/blister

Herpes Simplex

non-neoplastic; infectious
Cause: HSV
Risk: any
Manifestation: cold sores (HSV I) or genital herpes (HSV II)

Erythema Multiforme

non-neoplastic; infectious
Cause: HSV or drugs
Risk: any
Manifestation: target lesions

Molluscum Contagiosum (Water Warts)

non-neoplastic; infectious
Cause: poxvirus (MCV)
Risk: any
Manifestation: centrally umbillicated papules

Scabes

non-neoplastic; infectious
Cause: sarcoptes scabei
Risk: any
Manifestation: rash on skin folds

Urticana (Hives)

non-neoplastic; inflammatory
Cause: mast cell degranulation
Risk: any
Manifestation: erythemtous, edematous, pruntic

Psoriasis

non-neoplastic; inflammatory
Cause: inherited, genetic
Risk: any
Manifestation: itchy red lesions

Lichen Planus

non-neoplastic; inflammatory
Cause: immunity medication
Risk: any
Manifestation: purple polygonal papules
Wickham's strale

Atopic Eczema

non-neoplastic; inflammatory
Cause: inherited, genetic
Risk: any
Manifestation: itchy rash

Pemphigus Vulgaris

non-neoplastic; bullous Cause: antibodies attack intercellular junctions Risk: 40-50 years of age Manifestation: superficial bullae, mouth then skin (Tzanck's cells)

Bullous Pemphigold

non-neoplastic; bullous Cause: antibodies against basement membrane Risk: elderly Manifestation: big, subepidermal bullae of groin, axilla, arms and mouth

Nevus (mole)

Neoplastic; Benign Tumor Cause: benign proliferation of melanocytes Manifestation: depends on location

Hemanginoma

Neoplastic; Benign Tumor | common benign tumor of blood vessels

Keratoacanthoma

Neoplastic; Benign Tumor aberrant hair follicle crater like nodule can be a possible squamous cell carcinoma

Seborrheic Keratosis

Neoplastic; Benign Tumor benign epidermal tumor flat, brown, velvety plaque can be a sign of Leser-Trelat

Actinic Keratosis

Neoplastic; Benign Tumor benign neoplasm of epidermis rough spots with erythematous base on sun-exposed skin malignant if untreated

Basal Cell Carcinoma

Neoplastic; | malignant tumor of basal layer

Squamous Cell Carcinoma

Neoplastic; malignant | tumor of squamous epithelium

Kaposi Sarcoma

Neoplastic; vascular malignant tumor of lymphatic epithelium that intersects blood vessels would get red bumps AIDS patients and Ashkenazy Jews have higher incidence

Angiosarcoma

Neoplastic; vascular malignant tumor of endothelial type bruise-like patterns progressing to lesions

Peutz-Jeghers Syndrome

Neoplastic; vascular genetic mutation GI polyps and mucosal hyperpigmentation can lead to many malignancies