Skin Pathology - Bikman Flashcards
erythema
redness
macule
flat lesion
papule
raised lesion
plaque
large papule
vescicle
blister
acantholysis
loss of intercellular cohesion in keratinocytes
acanthosis
diffuse epidermal hyperplasia
hyperkeratosis
thick stratum corneum
papillomatosis
surface elevation by hyperplasia
Impetigo
non-neoplastic; infectious
Cause: staph. aureus or strep. phyogene
Risk: children
Manifestation: pustules
Erysipelas
non-neoplastic; infectious
Cause: Strep
Risk: anyone
Manifestation: erythematous plaque
Necrotizing Fasciitis
non-neoplastic; infectious
Cause: many
Risk: kids
Manifestation: gangrene
Acne
non-neoplastic; infectious
Cause: propionibacterium acne
Risk: varies
Manifestation: blocked sebaceous glands
Ringworm
non-neoplastic; infectious
Cause: fungi
Risk: anyone
Manifestation: red, scaly, brown, athletes foot
Sporotrichosis (Gardner’s Disease)
non-neoplastic; infectious
Cause: fungi
Risk: anyone
Manifestation: painless papule
Verruca Vulgaris
non-neoplastic; infectious
Cause: HPV
Risk: any
Manifestation: cauliflower formation/blister
Herpes Simplex
non-neoplastic; infectious
Cause: HSV
Risk: any
Manifestation: cold sores (HSV I) or genital herpes (HSV II)
Erythema Multiforme
non-neoplastic; infectious
Cause: HSV or drugs
Risk: any
Manifestation: target lesions
Molluscum Contagiosum (Water Warts)
non-neoplastic; infectious
Cause: poxvirus (MCV)
Risk: any
Manifestation: centrally umbillicated papules
Scabes
non-neoplastic; infectious
Cause: sarcoptes scabei
Risk: any
Manifestation: rash on skin folds
Urticana (Hives)
non-neoplastic; inflammatory
Cause: mast cell degranulation
Risk: any
Manifestation: erythemtous, edematous, pruntic
Psoriasis
non-neoplastic; inflammatory
Cause: inherited, genetic
Risk: any
Manifestation: itchy red lesions
Lichen Planus
non-neoplastic; inflammatory Cause: immunity medication Risk: any Manifestation: purple polygonal papules Wickham's strale
Atopic Eczema
non-neoplastic; inflammatory
Cause: inherited, genetic
Risk: any
Manifestation: itchy rash
Pemphigus Vulgaris
non-neoplastic; bullous
Cause: antibodies attack intercellular junctions
Risk: 40-50 years of age
Manifestation: superficial bullae, mouth then skin (Tzanck’s cells)
Bullous Pemphigold
non-neoplastic; bullous
Cause: antibodies against basement membrane
Risk: elderly
Manifestation: big, subepidermal bullae of groin, axilla, arms and mouth
Nevus (mole)
Neoplastic; Benign Tumor
Cause: benign proliferation of melanocytes
Manifestation: depends on location
Hemanginoma
Neoplastic; Benign Tumor
common benign tumor of blood vessels
Keratoacanthoma
Neoplastic; Benign Tumor
aberrant hair follicle
crater like nodule
can be a possible squamous cell carcinoma
Seborrheic Keratosis
Neoplastic; Benign Tumor
benign epidermal tumor
flat, brown, velvety plaque
can be a sign of Leser-Trelat
Actinic Keratosis
Neoplastic; Benign Tumor
benign neoplasm of epidermis
rough spots with erythematous base on sun-exposed skin
malignant if untreated
Basal Cell Carcinoma
Neoplastic;
malignant tumor of basal layer
Squamous Cell Carcinoma
Neoplastic; malignant
tumor of squamous epithelium
Kaposi Sarcoma
Neoplastic; vascular
malignant tumor of lymphatic epithelium that intersects blood vessels
would get red bumps
AIDS patients and Ashkenazy Jews have higher incidence
Angiosarcoma
Neoplastic; vascular
malignant tumor of endothelial type
bruise-like patterns progressing to lesions
Peutz-Jeghers Syndrome
Neoplastic; vascular
genetic mutation
GI polyps and mucosal hyperpigmentation
can lead to many malignancies
