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Dermatology (also gross but true) > Skin Manifestations of Systemic Disorders > Flashcards

Skin Manifestations of Systemic Disorders Flashcards

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Dermatology Board Prep flashcards
1
Q

Dermatologic manifestations seen with Crohn’s and ulcerative colitis

A

pyoderma gangrenosum and erythema nodosum

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2
Q

chronic and severely debilitating ulcerative skin disease. Painful hemorrhagic pustule surrounded by erythematous halo

A

pyoderma gangrenosum

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3
Q

Most common sites for pyoderma gangrenosum

A

lower extremities, butt, abdomen

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4
Q

Describe lesion that characterizes pyoderma gangrenosum

A

Irregular, boggy, blue-red ulcers with undetermined borders surrounding a purulent necrotic base

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5
Q

What can you use for high dose systemic corticosteroid treatment of pyoderma gangrenosum?

A

oral or IV prednisolone 1-2g per day. Can add intralesional triamcinolone

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6
Q

Systemic immunosuppression that can be effective in treating pyoderma gangrenosum

A

sulfasalazine, cyclosporine, infliximab

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7
Q

Skin condition associated with DM, obesity, internal malignancy (esp. GI)

A

acanthosis nigricans

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8
Q

Most common sites for acanthosis nigricans

A

axilla, neck, groin, antecubital fossae

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9
Q

Cutaneous disorder often associated with DM. Lesions are distinctive, sharply dircumscribed, multicolored (red, yellow, brown) plaques occurring on the anterior and lateral surfaces of the lower legs

A

Necrobiosis Lipoidica (NL), Diabeticorum

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10
Q

Treatment of Necrobiosis Lipoidica (NL), Diabeticorum

A

Refer. Topical steroids for ulcerations. May need excision and grafting

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11
Q

Self limiting, chronic dermatosis more common in older women characterized by smooth, shiny firm colored papules/plaques that are annular w/central depression

A

granuloma annular

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12
Q

Most common sites for granuloma annular

A

dorsum of hands/feet, extremities, and trunk

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13
Q

Percentage of patients with granuloma annular whose symptoms disappear in 2 yrs w/out treatment

A

75%. Can be treated w/potent topical and intralesional steroids

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14
Q

Usually occurs in areas of increased moisture at the site of infection, DM, or altered systemic immunity. Presents with erythema, tenderness, plaques, possible pruritis

A

intertrigo

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15
Q

Treatment for intertrigo if found to be caused by fungus

A

Dry area, wash with benzoyl peroxide or powder with miconazole daily

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16
Q

A candida infection occuring on the mucosa of the upper aerodigestive tract. Associated with HIV, DM, immunosuppression

A

thrush

17
Q

Treatment for thrush in a patient with a competant immune system

A

azoles/imidazoles

18
Q

Treatment for thrush in a patient who is immunocompromised

A

oral therapy-fluconazole 2-3 wks

19
Q

chronic, indolent skin disease associated with Lupus that is characterized by sharply marginated, scaly, atrophic, red (discoid) plaques primarily on face

A

chronic cutaneous (discoid)

20
Q

Treatment for chronic cutaneous (discoid) lupus

A

local corticosteroids, intralesional triamcinolone, and hydroxychloroquine

21
Q

Occurs in women 15-40 and is characterized by polycyclic scaly plaques in sun exposed areas. also associated with lupus

A

subacute cutaneous (cutaneous lupus erytheratosus)

22
Q

Condition characterized by butterfly” facial erythema which is nonscarring, Photosensitivity, Oral ulcers

A

lupus

23
Q

treatment for lupus and cutaneous lupus erytheratosus

A

antimalarials and immunosuppression

24
Q

Systemic disorder characterized by violaceous (heliotrope) inflammatory changes of the eyelids and periorbital area, photosensitivity, Gattron’s papules

A

dermatomysitis

25
Q

violaceous papules over knuckle prominences

A

Gattrons papules

26
Q

Treatement for dermatomyositis

A

steroids and methotrexate

27
Q

Name the components of CREST syndrome

A

calcinosis, Raynaud’s, esophageal dysmotility, sclerodactyly, telangiectasia

28
Q

Generalized sclerosis with internal organ involvement (heart, lungs, GI, kidney

A

progressive systemic sclerosis

29
Q

Lipid deposits in skin and tendons. Yellow-brown, pinkish, or orange macules/papules due to accumulations of macrophages containing droplets of lipids

A

xanthomas

30
Q

Conditions associated with xanthomas

A

hyperlipidemia, biliary cirrhosis, DM, CRF

31
Q

Where are tuberous xanthomas located?

A

over joints

32
Q

Most common of all xanthomas. When seen in children or young adults, it is associated with familial hypercholesterolemia

A

xanthelasma

33
Q

Multiple, longitudinal, creamy-orange, slightly elevated dermal papules on the eyelids of a normolipemic individual

A

xanthelasma

34
Q

Treatment of xanthomas

A

Laser, excision, electrodesiccation or topical application of trichloroacetic acid

Dermatology (also gross but true) (12 decks)

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