skin and wound healing Flashcards

1
Q

list function of skin

A

protection, regulation of body temperature, formation of vitamin D, cutaneous sensation, excretion, absorption

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2
Q

describe protection

A

non-specific defence mechanism
so a barrier against microorganisms
physical agents: melanocytes secrete melanin protect from ultraviolet
chemicals
dehydration

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3
Q

describe regulation of body temperature

A

heat production
heat loss: evaporation
conduction

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4
Q

describe formation of vitamin D

A

liquid based substance converted to vitamin d by sunlight

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5
Q

describe cutaneous sensation

A

sensory receptors, e.g. pacinian sensitive to touch, pain, temperature

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6
Q

describe excretion

A

NaCl in sweat
urea

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7
Q

explain changes to skin when ageing

A

skin becomes thin and fragile
fewer capillaries and cell proliferation decreases so slower wound healing
sensory receptors decline so increased susceptibility to injury and bruising appears frequently
skin appears dry and wrinkled as elastic fibres are reduced and collagen fibres become less flexible
melanocytes decrease causing greying of hair and skin

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8
Q

explain changes to skin developing foetus

A

epidermis develops from single layer of ectoderm
end of 4 weeks a thin outer layer of flattened cells covers embryo
adipose tissue develops from 17-20
>18 weeks fetus covered in protective layer called vernix caseosa
9-12th hair develops
fingernails and toenails 10-18 weeks

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9
Q

describe the mechanism of wound healing

A

inflammation of wound surfaces and blood clot and cell debris fill the gaps
clot becomes scab
proliferation: formation of granulation tissue (phagocytes, fibroblasts) restores blood supply to wound
maturation: fibrosis scar tissue replaces granulation tissue until full thickness restored

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