skin and wound healing Flashcards
list function of skin
protection, regulation of body temperature, formation of vitamin D, cutaneous sensation, excretion, absorption
describe protection
non-specific defence mechanism
so a barrier against microorganisms
physical agents: melanocytes secrete melanin protect from ultraviolet
chemicals
dehydration
describe regulation of body temperature
heat production
heat loss: evaporation
conduction
describe formation of vitamin D
liquid based substance converted to vitamin d by sunlight
describe cutaneous sensation
sensory receptors, e.g. pacinian sensitive to touch, pain, temperature
describe excretion
NaCl in sweat
urea
explain changes to skin when ageing
skin becomes thin and fragile
fewer capillaries and cell proliferation decreases so slower wound healing
sensory receptors decline so increased susceptibility to injury and bruising appears frequently
skin appears dry and wrinkled as elastic fibres are reduced and collagen fibres become less flexible
melanocytes decrease causing greying of hair and skin
explain changes to skin developing foetus
epidermis develops from single layer of ectoderm
end of 4 weeks a thin outer layer of flattened cells covers embryo
adipose tissue develops from 17-20
>18 weeks fetus covered in protective layer called vernix caseosa
9-12th hair develops
fingernails and toenails 10-18 weeks
describe the mechanism of wound healing
inflammation of wound surfaces and blood clot and cell debris fill the gaps
clot becomes scab
proliferation: formation of granulation tissue (phagocytes, fibroblasts) restores blood supply to wound
maturation: fibrosis scar tissue replaces granulation tissue until full thickness restored