Muscuoloskeletal System Flashcards

1
Q

What are the 5 basic tissues that make up the MSK system

A

Bones, ligaments, cartilage, skeletal muscles, tendons

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2
Q

Describe the basic function of ligaments

A

Attach bone to bone

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3
Q

Describe the basic structure of cartilage

A

Protective gel like substance lining joints and intervertebral discs (spine)
Shock absorber, protective mechanism- stop friction between bones

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4
Q

Describe the basic function of tendons

A

Attaching muscle to bone

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5
Q

What are the 5 bone types

A

Flat bones, e.g. sternum
Irregular bones, e.g. vertebrae
Sesamoid bones, e.g. patella
Long bones, e.g. Fermur
Short bones, e.g. carpals

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6
Q

Describe the skeletal system functions

A

Provide the body framework
Giving attachment to muscles and tendons
Alllowing movement of the body as a whole and parts, by forming joints that are moved by muscles
Forming boundaries if the carnium, thorax and pelvis and protecting the organs they contain
Haemopoiesis, the the production of blood cells in red bone marrow
Mineral storage, especially calcium phosphate - the mineral reservoir Whithorn nine is essential for the maintenance of blood calcium levels, which must be tightly controlled

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7
Q

Describe the spongy bone tissue

A

Porous
Highly vascularised
Function, reduces bone density,
allows end of long bones to compress as a result of repeated stress

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8
Q

Describe compact bone tissue

A

Makes up the hard outer layer, compact due to its minimal gaps and spaces
It gives bones their smooth, white and solid appearance, 80% of total bone mass
Contains nerves and blood vessels

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9
Q

Describe Long bones

A

Elongated , slender bones found mainly in the limbs
Made up of diaphysis (long shaft) and epiphysis (end bits)
And hyaline cartilage
Outer layer is tough/fibrous to protect bone underneath
Covered in vascular membrane (periosteum)
Inner layer contains bone cells for bone production and breakdown, repair and remodelling

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10
Q

Describe diaphysis

A

Composed of bone-central medullary canal containing fatty yellow bone marrow
Has own blood supply , main arterial nutrient supply to it

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11
Q

Describe epiphysis

A

Outer covering of compact bone with spongy bone inside
Has own blood supply

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12
Q

Describe the hyaline cartilage

A

Prevent damaging bone to bone contact

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13
Q

Describe the other bone structures

A

Flat bone and irregular bone made up of
thin outer layer of compact bone and
spongy bone inside containing red bone marrow
Surrounded by periosteum

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14
Q

Name the 3 types of bone cells

A

Osteoblasts
Osteocytes
Osteoclasts

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15
Q

Describe Osteoblasts

A

Bone building cells

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16
Q

Describe osteocytes

A

Mature bone cells

17
Q

Describe osteoclasts

A

Bone reabsorbing cells

18
Q

State function of osteoblasts

A

Deposit new bone tissue around themselves, eventually becoming trapped in tiny pockets in growing bones and differentiate into osteocytes

19
Q

State function of osteocytes

A

Do not divide
Responsible for bone formation and calcium homeostasis

20
Q

State function of osteoclasts

A

Breakdown bone releasing calcium and phosphate
As new bone cells are made, old ones are destroyed by osteocytes

21
Q

Describe stage 1 of Osteogenesis

A

Stage 1: osteoblasts secrete osteoid (proteins)
Replace cartilage in foetus

22
Q

Describe stage 2 of osteogenesis

A

Calcium and phosphate laid down
Osteoblasts progressively calcify it converting the cartilage into a hard rigid mature bone

23
Q

Describe stage 3 of osteogenesis

A

Osteoblasts form a matrix, cells become trapped and become osteocytes

24
Q

Describe the role of HGH, Thyroxine and tri-iodothryronine

A

Promote bone growth in foetus

25
Describe the role of testosterone and oestrogen in bone growth
Testosterone- increase bone mass Oestrogen- increase bone density
26
Describe the role of calcitonin and parathyroid in bone growth
Calcitonin- increases uptake of calcium Both calcitonin and parathyroid control calcium uptake and ensuring bone density is maintained Parathyroid- decreases uptake of calcium
27
How do we maintain our bones
Bones constantly being remodelled and regrown due to continued wear and tear and trauma
28
1st stage of bone healing
Haematoma formation Big blood clot Stops active bleeding
29
2nd stage of bone healing
Callus formation Fibroblasts and osteoblasts lay down granulation tissue and osteoid tissue Phagocytosis of dead bone and tissue fragments by macrophages
30
3rd stage of bone healing
Bony Callus formation Callus laid done as spongy bone and brings together ends of broken bones Supports and splints fracture
31
4th stage of bone healing
Recanalisation and remodelling Converts the external callus to compact bone