Skin and temperature regulation Flashcards

1
Q

What is meant by man being homeothermic?

A

likes to keep body temperature around the same point

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2
Q

Core body temp

A

37+/-0.5

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3
Q

What happens if body temperature is above 41?

A

denature proteins

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4
Q

What happens if body temperature is below 30?

A

lose consciousness

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5
Q

List 4 things body temperature varies with

A

menstrual cycle
circadian rhythm
external temperature
activity

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6
Q

What is the biggest source of heat loss?

A

radiation

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7
Q

What receptors detect temperature changes?

A

cold and warm thermoreceptors

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8
Q

Where are peripheral thermoreceptors found?

A

skin eg face and scrotum

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9
Q

Where are central thermoreceptors found?

A

spinal cord, abdominal organs and hypothalamus

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10
Q

4 ways in which heat generated increases

A

metabolism
muscle activity
shivering thermogenesis
non shivering thermogenesis

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11
Q

Who is non shivering thermogenesis important in and why?

A

infants - brown adipose tissue

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12
Q

2 ways in which heat loss is decreased

A

vasomotor - sympathetic arteriolar constriction

behaviour eg add clothes

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13
Q

Define hypothermia

A

A fall in deep body temperature to below 35 degrees

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14
Q

Who is at risk of hypothermia?

A

neonates
elderly
vagrants
outdoor

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15
Q

Treating hypothermia

A

dry/insulate
slow rewarming with blankets
internal re-warming with hot drinks
fast re-warming by immersion in water

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16
Q

Vascular frostbite

A

vasoconstriction, increase in viscosity and thrombosis leading to anoxia

17
Q

Cellular frost bite

A

ice crystals form in ECF
increase ECF osmolarity
move water into space leading to cell dehydration and death

18
Q

Why is there more strokes and heart attacks in winter?

A

increased vasoconstriction and increased blood viscosity

19
Q

2 ways in which heat production is minimised

A

decrease physical activity

decrease food intake

20
Q

3 ways heat loss increased from body

A

vasomotor control - arteriolar dilation
sweating
behaviour eg remove clothes and increase surface area

21
Q

What temperature does heat exhaustion occur?

A

37.5-40 degrees

22
Q

What happens in heat exhaustion?

A

vasodilation and drop in central blood volume

excess sweating disturbs water and salt balance

23
Q

Symptoms of heat exhaustion

A

headache, confusion, nausea, profuse sweating, clammy skin, tachycardia, hypotension, weak pulse, fainting and collapse

24
Q

Heatstroke body temperature

25
Symptoms of heat stroke
hot dry skin and circulatory collapse
26
Most at risk groups of heat stroke
neonate and elderly physical work in hot climate non-breathable protective clothing
27
Treatment of heat stroke
``` move to cool environment remove clothing fan sponge with slightly warm water give fluids - IV and oral ```
28
What causes fever?
endogenous pyrogens
29
What happens to produce fever in infection and explain why paracetomol works
cyclo-oxygenase in hypothalamus produces prostaglandins paracetomol blocks this enzyme Body temperature set around a higher temp endogenous pyrogens shift the set point