Benign and pre-malignant skin conditions Flashcards

1
Q

What cells are seborrheic keratosis derived from?

A

keratinocytes

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2
Q

Appearance of seborrheic keratosis

A

warty growths with a stuck on appearance
variable
multiple angiomas

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3
Q

How are seborrheic keratosis treated?

A

usually left unless problematic and then would do cryotherapy or curettage

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4
Q

What is cryotherapy?

A

freeze with liquid nitrogen

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5
Q

pros of cryotherapy

A

cheap and easy to perform on the day

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6
Q

Cons of cryotherapy

A

scar, failure/recurrence and no pathology result

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7
Q

What is leser trelat?

A

paraneoplastic

abrupt onset of widespread seborrheic keratosis

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8
Q

What can leser trelat signify?

A

underlying solid organ malignancy eg GI adenocarcinoma

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9
Q

What is the cause of viral warts?

A

HPV

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10
Q

Treatment of viral warts

A

not treated in children
clear when immunity develops
cryotherapy or wart paints can stimulate immune system slightly
curette if severe

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11
Q

Define a cyst

A

encapsulated lesion containing fluid or semi-fluid material

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12
Q

How do cysts feel?

A

firm and fluctuant

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13
Q

List some types of cysts

A
epidermoid 
pilar 
dermoid 
steatocystoma 
hidrocystoma 
ganglion
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14
Q

Treatment of cyst and what to do if it becomes infected

A

excision

antibiotics, intralesional steroid, incision and drain

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15
Q

What is a dermatofibroma?

A

benign fibrous nodule often on limbs due to proliferation of fibroblasts

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16
Q

Appearance of deramtofibroma

A

firm nodule, tethered to skin but mobile over fat

pale pink/brown - paler in centre

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17
Q

What test is positive in dermatofibroma?

A

dimple sign

18
Q

Management of dermatofibroma

A

asymptomatic usually but may be itchy or tender but if symptomatic can excise

19
Q

Define lipoma

A

benign tumour of fat cells

20
Q

Texture of lipoma

A

smooth and rubbery subcutaneous mass

21
Q

What would you be considering if a lipoma is tender?

A

angiolipoma

liposarcoma

22
Q

What is an angioma?

A

overgrowth of blood vessels in the skin due to proliferating endothelial cells

23
Q

Groups of people angiomas are found in

A

all ages

pregnancy and liver disease

24
Q

Appearance of pyogenic granuloma

A

Rapidly enlarging red raw growth at site of trauma

bleed

25
Treatment of pyogenic granuloma
curettage and cautery
26
Risk factors of pre-malignant conditions
UV radiation and immunosuppression
27
Appearance of actinic keratosis
rough scaly patches on sun damaged skin
28
Treatment of actinic keratosis
cryotherapy, curettage, diclofenac gel and imiquimod
29
What is the risk of actinic keratosis transforming into SCC?
low
30
What is bowen's disease?
intraepidermal SCC
31
Appearance of bowmans disease
irregular scaly erythematous plaque
32
Treatment of bowen's disease
cryotherapy curettage photodynamic therapy imiquimod
33
What does photodynamic therapy do?
kill cancer cells
34
Pros of photodynamic therapy
done for patient by hospital staff can treat multiple areas 1 or 2 areas
35
Cons of photodynamic therapy
requires hospital admission | can be painful and scar
36
What does imiquimod do?
immune response modifier which stimulates cytokine release and destroys lesion
37
Pros of imiquimod
Useful when surgery undesirable good cosmetic result large SA
38
Cons of imiquimod
treatment time 6 weeks inflammation failure/recurrence do it themselves
39
Management of melanoma in situ
cannot metastasises - confined to epidermis | excise and educate on checking skin
40
Name a type of melanoma in situ usually found on the face
lentigo maligna
41
If a patient came asking for advice on sun exposure what would you tell them?
``` cover up avoid 10am-4pm wear atleast SPF 30 do not burn and try to not tan avoid sunbeds UVA+UVB protection 2 tablespoons every 2 hours ```