Skin Flashcards

1
Q

Functions of the skin

A
  • protection
  • homeostasis
  • sensory
  • endocrine
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2
Q

Protection

A

Barrier, immunologic

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3
Q

Homeostasis

A

Fluid, thermoregulation, excretory

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4
Q

Layers of the skin

A
  • epidermis: epithelial layer
  • dermis: underlying connective tissue
  • subcutis: panniculus, hypodermis
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5
Q

Epidermal derivatives

A
Adnexa: extra structures
- hair
- nails
- hooves
- glands
Derived from the stratum basale of the epidermis and embedded in the dermis
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6
Q

Epidermis

A
  • Stratified squamous epithelium (keratinocytes)
  • Melanocytes (pigment)
  • Langerhans’ cells (antigen presentation)
  • Merkel cells (sensory)
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7
Q

Keratinocytes

A

Matured cells that have lost their nucleus become keratin debris at the top

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8
Q

How many pigments do mammals produce?

A

1, black

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9
Q

Epidermis Appendages

A
  • hair
  • glands
  • nails/hooves
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10
Q

Epidermal appendages are also called ____

A

Adnexa

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11
Q

Types of skin glands

A
  • Sweat (eccrine, apocrine)
  • Mammary
  • Sebaceous (sebum)
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12
Q

Can you tell nails and hooves apart histologically?

A

No, both are keratinized structures

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13
Q

What are glands lined by?

A

Cuboidal epithelium

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14
Q

Layers of the epidermis

A
  • S. corneum
  • S. lucidum: not present in non-human mammals
  • S. granulosum: see granularity in the cytoplasm
  • S. spinosum: start to see spaces
  • S. basale (germinativum): layer on the basement membrane
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15
Q

Strata vs stratum

A

Strata: 5 layers of the epithelium
Stratum: 1 layer

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16
Q

Dermis

A
  • Hemidesmosomes
  • Dermal papillae (epidermal rete ridges)
  • Dermal ridges (thick skin)
  • Papillary and reticular layers
17
Q

Deep rete ridges

A

Increases interface between dermis and epidermis

- occurs in areas of wear and tear

18
Q

Subcutis/hypodermis

A
  • Loose reticular connective tissue

- Adipose connective tissue

19
Q

Where do you give sub q injections?

A

In the loose reticular connective tissue

- want to go past the dermis into the subcutis