Sketchy

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Answer 1

ANTIEMETIC AGENTS:

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Answer 2

h2 receptor blockers and ppi’s

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Answer 3

laxatives and antidiarrheal agents

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Answer 4

diabetic drugs

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Answer 5

metformin

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Answer 6

propylth…

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Answer 7

bisphos…

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Answer 8

teriparatide

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Answer 9

glucocorticosteriods

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Answer 10

adh, DDAVP

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Answer 11

growth hormone

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Answer 12

Methotrexate

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Question 15

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Answer 17

Doxorubicin’s Locker: Antineoplastic antibiotics

Bleomycin: Beluga whale - Oxide bubbles: bleomycin binds DNA and produces free radicals (superoxide and hydroxide) , broken double helix kelp. free radicals produced cause single and doule stranded breaks in the DNA. Galleon: Blocks the G2 phase of the cell cycle. Cracked anticancer crab:Treats many hematologic and solid malignancies (E.g. Hodkin and Non-hodgkin lymphoma, germ cell tumors, squamous cell carcinoma of the skin, cervix and vulva. It can cause Pulmonary toxicity (e.g. Pneumonitis, pulmonary infliltrates on Xray)-Lung coral. Hyperpigmented striae: It can cause skin toxicity (e.g. rash, exfoliation, hyperpigmentation, atrophic striae. Poking mouth: bleomycin (and anthracyclines) can cause mucositis and stomatitis. Bald beluga: can cause alopecia.

Anthracyclines: (Santa Athracycline)

Rubies: “-rubicin” suffix of antracyclines (e.g. doxorubicin and daunorubicin)

Oxide bubbles: produce free radicals

Rubies inserting into helical seaweed: anthracyclines (e.g. doxorubicin) intercalates in DNA –> block DNA and RNA synthesis.

Chelating the heart sack: dexrazoxane (iron chelator) prevents antracycline-induced cardiotoxicity.

Up on deck with razor: dexrazoxane (iron chelator)

Depleted bone chest: anthracyclines (doxorubicin) and actinomycin D can cause myelosupression.

Poking mouth: bleomycin (and anthracyclines can cause mucositis and stomatitis.

Bald pirate: antracyclines (e.g doxorubicin) can cause alopecia)

Doxorubicin:

Cracked cancer crab: treats a broad range of solid and hematologic malignancies.

Dilated heart ruby sacks: anthracyclines (e.g.doxorubicin) can cause cardiotoxicity (e.g. dilated cardiomyopathy)

Daunrubicin

Actinomycin D/ Dactomycin:

Doll artifact

Artifacts inserting into helical seaweed: actinomycin D intercalates in DNA–> blocking dna AND RNA synthesis

Child’s artifact: actinomycin D treats numerous pediatric malignancies (e.g Wilms tumor, Erwing sarcoma, rhabdomyosarcoma).

Bald doll: can cause alopecia

Depleted bone chest: can cause myelosupression