A13. Centrally acting skeletal muscle relaxants (spasmolytics). Dantrolene. Botulinum toxin

Question 1

List the centrally acting muscle relaxants.

Answer 1

1) Baclofen

2) Gauifenesin

3) Chlorzoxazone

4) Cyclobenzaprine

5) Drugs for acute spasm + spasticity:

• Benzodiazepines: Diazepam
• Tizanidine
• Tolperisone
• Carisoprodol

Question 2

List the Peripheral muscle relaxants.

Answer 2

1) Dantrolene

2) Botulinum

3) Aminoglycosides

4) Drugs acting on the NMJ: curare drugs, succinylcholine.

Question 3

Baclofen

Answer 3

MOA?