Skeletal Muscle Relaxants Flashcards
1
Q
Non-depolarizing agents
A
- competitive inhibitors/antagonists
- block ACH at nicotinic receptor
- prevent depolarization
2
Q
Depolarizing agents
A
- agonists
- inhibit by creating excessive depolarization
3
Q
Rocuronium
A
- aminosteroid non-depolarizing NM-blocking agent
- rapid onset/intermediate duration
- used for intubation and relaxation during surgery
4
Q
Vecuronium
A
- non-depolarizing NM-blocking agent
- rapid onset/intermediate duration
- used for intubation/relaxation during surgery
- no change in HR/BP
5
Q
Papaverine
A
- anti-spasmolytic
- treats vasospasm and HTN
- prevents LIMA spasm in CABG
6
Q
Dantrolene
A
- sarcoplasmic reticulum Ca+ channel blocker
- muscle relaxant
- treats malignant hypothermia
7
Q
Dantrolene dosage for MH treatment
A
- 1.0 - 2.5 mg/kg initial dose
- up to 10 mg/kg
