Anti-inflammatory/Immunosuppressants

Question 1

NSAIDs

Answer 1

• anti-inflammatory
• antipyretic
• analgesic

Question 2

Salicylates - Aspirin

Answer 2

• inhibits COX2 pathway

- NSAID

Question 3

Propionic acid - Ibroprofin

Answer 3

• NSAID

- Less GI effects

Question 4

Acetaminophen

Answer 4

• not an NSAID

- antipyretic and analgesic

Question 5

Cyclosporin

Answer 5

• immunosuppressant
• prevents rejection during transplants
• Down regulates IL-2 release from T/B cells

Question 6

Tacrolimus

Answer 6

• immunosuppressant
• prevents rejection of liver and kidney transplants
• given with corticosteroid or antimetabolite

Question 7

Sirolimus

Answer 7

• immunosuppressant
• doesn’t allow immune cells to bind
• used to coat stents

Question 8

Corticosteroids

Answer 8

• suppress T lymphocytes

- used in combination with immunosuppressants