Antibiotics Flashcards

1
Q

Types of antibiotics

A
  • cell wall synthesis
  • cell membrane function
  • metabolism
  • protein synthesis
  • DNA synthesis
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2
Q

Cell wall inhibitors

A
  • PCN
  • Cephalosporins (Ancef)
  • Vancomycin
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3
Q

PCN

A
  • cell wall inhibitor
  • b-lactam
  • prevents peptidoglycan synthesis in wall
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4
Q

Cephalosporins

A
  • cell wall inhibitor
  • more resistant to b-lactamase
  • interferes with peptidoglycan synthesis
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5
Q

Vancomycin

A
  • cell wall inhibitor

- NOT b-lactam

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6
Q

Protein synthesis inhibitors

A
  • Tetracyclines

- Aminoglycosides (-mycin)

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7
Q

Tetracyclines

A
  • protein synthesis inhibitor
  • bacteriostatic
  • block binding of tRNA to mRNA
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8
Q

Aminoglycosides (-mycin)

A
  • protein synthesis inhibitor
  • treat gram negative
  • causes incorrect reading of mRNA
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9
Q

DNA synthesis inhibitors

A
  • fluroquinalones

- sulfonamides

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10
Q

fluroquinolones

A
  • DNA inhibiting antimicrobial
  • bactericidal for both gram + and -
  • enter through porin
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11
Q

sulfonamides

A
  • DNA inhibiting antimicrobial

- inhibits production of folate

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12
Q

Antifungals

A

-damage ergestaril in cell walls

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13
Q

Neuraminidase inhibitors

A
  • antiviral
  • prevent viral replication
  • used for influenza and RSV
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14
Q

NRTI

A
  • antiviral

- nucleoside reverse transcriptase inhibitors

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15
Q

NNRTI

A
  • antiviral

- non-nucleotide reverse transcriptase inhibitor

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