SIRS/Sepsis

Question 1

Systemic Inflammation Response (SIRS)

Answer 1

Exadurated response to a stressor or trauma, infection, acute inflammation
Non-specific infection

Question 2

SIRS Criteria

Answer 2

HR > 90 BPM
RR > 20 BPM
Temp > (or equal to) 38 OR < 36
WBC > 12.0 or < 4.0 x 10 g/L
Altered mental status (<15 GCS)

Question 3

Key interventions of SIRS/sepsis

Answer 3

1. Labs and diagnostics
2. IV fluids
3. Antibiotics
4. monitoring criteria

Question 4

SEPSIS

Answer 4

If suspected or known pathogen is identified

Suspected or confirmed source of infection + SIRS criteria

Question 5

Risk factors of SIRS and suspected source of infection

Answer 5

Increased or decreased age
immunosuppressant drugs
comorbidity
Invasive meds or treatments

Question 6

Severe Sepsis

Answer 6

patient is showing signs of hypoperfusion to one organ system

causes multiorgan failure

(sepsis + hypoperfusion to 1 organ)

Question 7

Septic Shock

Answer 7

severe sepsis with hypotension that does not resolve despite IV fluid resuscitation

Question 8

Labs and Diagnostics

Answer 8

Blood culture (local or systemic infection?)
serum lactate (chemical naturally produced by the body to fuel cells during times of stress)

Question 9

IV fluids

Answer 9

IV bolus, secondary IV access

Make sure to repeat VS and chest ausc. prior and following each fluid bolus

Question 10

Antibiotics

Answer 10

Wait 30 minutes before administering IV antibiotics if the blood culture isnt ready yet