Reproductive Disorders - M Flashcards
Benign hyperplasia (BPH)
Non-inflammatory enlargement of prostate gland resulting from increase in # of epithelial cells and amount of stromal tissue
BPH - Patho
Endocrine changes with aging
Develops in the inner part of prostate that compresses urethra (can cause complete obstruction)
Ways to reduce susceptibility to BPH
Diet of fruit and veg
Physical activity
BPH - Clinical Manifestations
Obstructive: Decrease in force of urinary stream, hesitancy, dribbling
Irritative: Frequency, urgency, dysuria, pain, incontinence
BPH - Care
Watchful waiting
Drug therapy
Minimally invasive therapy
Invasive therapy
BPH Drug therapy
5 a-Reductase inhibitors (proscar)
a-Adrenergic receptor blockers (rapaflo)
Erectogenic Drugs (Tadalafil)
BPH Minimally invasive therapy
TUMT TUNA Laster prostatectomy TUVP Urethral stents
BPH Invasive therapy
TURP (gold standard)
TUIP
Prostatectomy
Manage symptoms of BPH by…
decrease alcohol and caffeine
limit cold and cough meds
maintain normal fluid intake levels
urinate on 2-3 hour schedule
Prostate cancer
Malignant tumor of prostate gland
Outer aspect of prostate
Androgen-dependent adenocarcinoma
Prostate cancer risk factors
>50 black>white>asian high levels of testosterone Diet high in fats and low in fruits and veg Occupation exposure to cadmium
Prostate Cancer - Manifestations
Generally asymptomatic during early stages
Urinary symptoms *diff starting or stopping urination, slow stream, pain, dribbling, frequency, loss of control, blood in urine, nocturia)
Prostate Cancer - Diagnosis
DRE (gold standard)
Prostate cancer - tx
Most tx have undesirable side effects
- Hormonal side effects
- specific surgical side effect (dribbling, impotence)
- Chemotherapy and radiation therapy side effect (N/V, fatigue)
