F & E Flashcards
Body fluid compartments
Intracellular
Extracellular
Transcellular
Intracellular (ICF)
Fluid inside cells (2/3 of fluid)
Low in Na
High in K
Extracellular (ECF)
Fluid outside of cells (1/3 of fluid)
2 components:
- plasma (intravascular)
- between cells (interstitial and lymph)
Transcellular
CSF, GI tract and pleural, synovial, peritoneal spaces
Can become a “third space”
Diffusion
molecules move from high to low concentration through permeable membrane
No energy required
Facilitated diffusion
Movement of molecules from high to low concentration without energy
Uses specific protein carrier molecules to accelerate diffusion across the cell membrane
Active transport
Process in which molecules move against concentration gradient
External energy needed
Osmosis
Movement of water between two compartments by a membrane permeable to water but not to solute
Moves from low to high solute concentration
No energy
Osmotic Pressure
Amount of pressure required to stop osmotic flow of water
determined by concentration of solutes in solution
high osmolality = high concentration
Hydrostatic pressure
force within a fluid compartment
Major force that pushes water out of vascular system at capillary level
Arterial end is high (fluid out)
Venous end will have lower (fluid in)
Oncotic pressure
Osmotic pressure exerted by colloids in solution
Protein is major colloid
Third spacing
Phase 1: Fluid moves out of intravascular space, lymphatic system is unable to compensate, fluid gets trapped in body spaces, risk of intravascular FVD with S and S of dehydration
Phase 2: Fluid moves back into intravascular space, risk for intravascular FVE (lead to HF)
Edema
Plasma to interstitial fluid results in edema
Elevation of hydrostatic pressure
Decrease in plasma oncotic pressure
Elevation of interstitial oncotic pressure
Cause = Changes in pressures or proteins
Compression stockings
decreases peripheral edema by increasing tissue hydrostatic pressure
Water deficit
increased ECF osmolality
associated with symptoms that result from cell shrinkage as water is pulled into vascular system