Sexually Transmitted Infections Flashcards
The causative organism for gonorrhoea is
Neisseria gonorrhoeae
Gonorrhea diagnosis involves _____ and/or ______ of the affected clinical site(s)
culture testing and/or NAAT
Gonorrhea can be symptomatic or asymptomatic
Males initially present with ______ associated with dysuria
Females present ________
purulent discharge
asymptomatically
Preferred treatment for gonorrhea non-MSM
Ceftriaxone + Azithromcyin
Cefixime + Azithromcyin
Duration is 1 dose
Preferred treatment for gonorrhea (pharyngeal in any population or if MSM)
Ceftriaxone + Azithromycin
Duration is 1 dose
Gonorrhoea “TEST OF CURE” is recommended after completion of therapy, especially in the following settings:
1.
2.
3.
etc
- pregnancy
- child
- not treated with ceftriaxone
disseminated infection, tx failure, resistance, pharyngeal infection
After completing therapy for Gonorrhoea:
culture based tests should be done __ - __ days after treatment
NAAT tests should be completed __ - __ weeks after treatment
3-7 days
2-3 weeks
Chlamydia and gonorrhea
Refer all recent (<___ days) partners for testing and empiric treatment ); no sexual contact for patient or other affected individuals until __ week after initiation of treatment
60 days
1 week
Chlamydia is caused by
Chlamydia trachomatis
Chlamydia is generally asymptomatic however severe disease including ____ produces potentially invasive infections
LGV (Lymphogranuloma venereum)
Females are typically more symptomatic than males for Chlamydia and present with:
List some symptoms
Cervicitis, vaginal discharge, dysuria, lower abdominal pain, abnormal vaginal bleed, dyspareunia, conjunctivitis
Preferred treatment for uncomplicated chlamydia
1
2
1 Azithromycin PO x 1 dose
OR 2 doxycycline BID x 7 days
Preferred therapy for pregnant, or uncomplicated chlamydia
1
2
Amoxicillin po tid x 7 days OR azithromycin PO x 1 dose
Treatment for severe, LGV chlamydia
1
2
Doxycycline x 21 days OR erythromycin x 21 days
Test of cure for Chlamydia is not recommended after completion of therapy unless:
1
2
3
4
1 adherence concerns
2 alternative therapy used
3 concerns for child abuse
4 pregnancy
NAAT tests for chlamydia should be completed __ - __ weeks after treatment
3-4
Syphilis is caused by the spirochete _______
Treponema pallidum
What are the 3 stages of syphilis clinical presentation
1
2
3
Primary
- painless chancre on cutaneous or mucocutaneous tissue at the original site of infection
Secondary (2 weeks- 6 months)
- rash, fever, malaise, swollen lymph nodes, wax and wane symptoms
Tertiary (years)
- Systemic involvement, bones, CNS, heart, blood vessels, liver, SSTI, eyes
What is the preferred therapy for early stage: primary, secondary or latent under 1 year of syphilis ?
Benzathine PEN G IM x 1 dose
(if true penicillin allergy and failed alternative treatments patient must be desensitized)
ALT: Doxy
Ceftiraxone
Preferred therapy in late stage syphilis?
Benzathine PEN G IM x 3 doses weekly
(if true penicillin allergy and failed alternative treatments patient must be desensitized)
ALT: Doxy x 14d (28 late)
Ceftiraxone x 10d
Patient with ocular syphilis should be treated with ?
PEN G IV x10-14 d
True or False: Test of cure is recommended after therapy in syphilis?
True
Sexual partners require assessment and treatment relative to the stage of syphilis:
Primary: partners within _______
Secondary: partners within ______
Early latent: partners within______
3 months
6 months
1 year
Patient administrable medication for HPV treatment?
1
2
1 podofilox 0.5%
2 imiquimod 3.75% or 5% cream
MD administered
- podophyllin 10-25%
- cryotherapy
HPV vaccine is not recommend for
1
2
1 females < 9 years
2 pregnancy
