Diarrhea Flashcards
What are the 3 types of diarrhea
Acute <14 days
Persistent 14 days up to 4 weeks
Chronic >4 weeks but symptoms less severe
Diarrhea is a change in normal bowel movements with the following characteristics
1.
2.
3.
- increased water content
- increased volume
- increased frequency, > or equal to 3 loose stools/day
List some examples of drug related signs and symptoms of diarrhea
1.
2.
3.
- recent abc use
- PPI
- Laxative use
Magnesium based antacids, sorbitol containing drugs, orlistat, motility agents ex domperidone
3 Common risk factors ?
- Travel
- Age ( very old or <3)
- Recent abx use or unsafe sexual practice
Some red flags for any type of diarrhea?
- signs and symptoms of dehydration
- severe diarrhea (> 6 loose stools per day) for > 48 hrs (adults) and > 24 hours (children)
- blood
- pain
- fever >38.5
- persistent or chronic diarrhea
- vomiting >4hrs
recent abx use associated with C.Diff (Clindamycin, ampicillin, cephalosporins) - Immunocompromised
- PREGNANCY
- < 2 YO
What are some signs of dehydration in children?
- dry mouth
- little or no tears
- <4 wet diapres in 24 hours
- sunken eyes or cheeks
- tired irritable
- decreased skin turgor
Non-Pharm options for any type of diarrhea?
- ORT
- Avoid caffeine, alcohol, sugary beverages
- if infectious avoid loperamide (prevents removal of toxin from bowel)
- report outbreaks
- prevention via vaccine, frequent hand wash, traveler diarrhea education
What are the treatment options for acute diarrhea?
- Bismuth subsalicylate
- Loperamide
Acute diarrhea should not be treated with _________ unless travellers’ diarrhea
empiric abx
Bismuth subsalicylate should be avoided in
1.
2.
3.
- children <12
- pregnancy
- breastfeeding
in patients taking anticoagulants, methotrexate, and salicylates
Caution if someone has a true allergy to ASA, they could develop an allergic response to ______
Pepto Bismol (Bismuth Subsalicylate)
Bismuth subsalicylate can cause ______ stools
black tarry
Loperamide is not recommended for use in patients with ______ or ______
bloody diarrhea or fever
Loperamide should be avoided in children _____
< 2 years of age
Loperamide can be used in _______ and _______ (a certain population)
pregnancy and breastfeeding
Loperamide dosing:
4 mg STAT, 2 mg after each loose BM, max 16 mg /day
Loperamide should be discontinued if diarrhea persists > ____ hours
48 hours