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Step 1 Review > Serum tumor markers > Flashcards

Serum tumor markers Flashcards

1
Q

Alkaline Phosphatase

A

Metastases to bone or liver
Paget Disease of the bone
Seminoma

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2
Q

AFP

A 
Hepatocellular Ca 
Yolk Sac Tumor(endodermal sinus)
Mixed Germ Cell Tumor
Ataxia Telangiectasia
Neural tube defects
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3
Q

hCG

A

Hydatidiform moles
Choriocarcinomas
Testicular Ca
Mixed germ cell tumor

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4
Q

CA 15-3

CA 27-29

A

Breast Ca

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5
Q

CA 19-9

A

Pancreatic adenocarcinoma

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6
Q

CA 125

A

Ovarian Ca

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7
Q

Calcitonin

A

Medullary Thyroid Ca (alone and in MEN2A, and MEN2B)

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8
Q

CEA

A

Colorectal and pancreatic Ca

Minor associations: gastric, breast, and medullary thyroid Ca

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9
Q

Chromogranin

A

Neuroendocrine tumors

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10
Q

LDH

A

Testicular germ cell tumors

Ovarian dysgerminoma

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11
Q

Neuron-specific enolase

A

Neuroendodrine tumors: Small cell lung Ca, Carcinoid tumor, Neuroblastoma.

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12
Q

PSA

A

Prostate Ca

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13
Q

S-100

A

Melanoma

Neural Crest Tumors

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Step 1 Review (14 decks)

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