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Step 1 Review > Autoantibodies > Flashcards

Autoantibodies Flashcards

1
Q

Anti-phospholipid Syndrome

A

Anti- ß2 glycoprotein I
Anti-Cardiolipin
Lupus anticoagulant

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2
Q

SLE

A 
Anti-Smith
Anti- dsDNA
Antinuclear Antibody (ANA) - nonspecific
Anticardiolipin
Lupus anticoagulant
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3
Q

Mixed Connective Tissue Disease

A

ANti-U1RNP

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4
Q

Polymyositis

Dermatomyositis

A

Anti-Jo1 (Anti-synthetase)
Anti-SRP
Anti-helicase (Anti-Mi-2)

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5
Q

Type 1 DM

A

Anti-glutamic acid decarboxylase

Islet cell cytoplasmic antibodies

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6
Q

Celiac Disease

A

IgA Anti-endomysial
IgA Anti-tissue transglutaminase
IgA & IgG deaminated gliadin peptide

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7
Q

Pernicious Anemia

A

Anti-parietal cell

Anti-intrinsic factor

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8
Q

Limited Scleroderma (CREST)

A

Anti-centromere

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9
Q

Autoinmune Hepatitis type I

A

Anti-Smooth muscle

Anti-liver/kidney microsomal-1

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10
Q

Good Pasture Syndrome

A

Anti-glomerular BM

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11
Q

MG

A

Anti-postsynaptic Ach receptor

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12
Q

Lambert-Eaton Sx.

A

Anti-presynaptic voltage gated Ca+ channel

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13
Q

Ulcerative Colitis

A

MPO-ANCA/p-ANCA

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14
Q

Pemphigous Vulgaris

A

Anti-desmoglein (desmosome)

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15
Q

Bullous Pemphigoid

A

Anti-hemidesmosome

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16
Q

Granulomatous with Polyangiitis (Wegener)

A

PR3-ANCA/c-ANCA

17
Q

1˚ Membranous Nephropathy

A

Anti-Phospholipase A2 receptor

18
Q

Microscopic Polyangitis

A

MPO-ANCA/p-ANCA

19
Q

Eosinophilic Granulomatosis with polyangitis (Churg-Strauss)

A

MPO-ANCA/p-ANCA

20
Q

1˚ Biliary Cholangitis

A

Anti-mitochondrial

21
Q

Rheumatoid Arthritis

A 
Rheumatoid Factor (IgM antibody against IgG Fc region)
Anti-CCP (more specific)
22
Q

Drug induced lupus

A

Ant-histone

23
Q

Hashimoto Thyroiditis

A

Anti-thyroglobulin

Anti-thyroid peroxidase (antimicrosomal)

24
Q

Graves Disease

A

Anti-TSH receptor

Step 1 Review (14 decks)

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