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Step 1 Review > Important histology > Flashcards

Important histology Flashcards

1
Q

Papillary Thyroid Ca

A

Orphan Annie eyes = Empty-appearing nuclei (containing finely dispersed chromatin) with central clearing
Psamomma bodies
Nuclear grooves

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2
Q

Follicular Thyroid Ca

A

Colloid containing micro-follicles + invasion of capsule

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3
Q

Medullary Thyroid Ca

A

Sheets of polygonal cells or spindle shaped cells with extracelullar amyloid deposition (stains with congo red)

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4
Q

Undifferentiated/Anaplastic Thyroid Ca

A

Markedly pleomorphic cells, including irregular giant cells and biphasic spindle cells

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5
Q

Graves disease

A

Tall, crowded follicular epithelial cells with scalloped colloid
DIFFUSE radioiodine uptake

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6
Q

Toxic multinodular goiter

A

FOCAL patches of hyperfunctioning follicular cells distended with colloid

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7
Q

Hashimoto disease

A

Hürthle cells (eosinophilic epithelial cells)

Lymphoid aggregates with germinal centers

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8
Q

Subacute granulomatous thyroiditis (de Quervain)

A

Granulomatous inflammation (multinucleated giant cells)

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9
Q

Riedel Thyroiditis

A

Thyroid replaced by FIBROUS tissue with inflammatory infiltrate

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Step 1 Review (14 decks)

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