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Block 2 Drugs > Serotonin > Flashcards

Serotonin Flashcards

1
Q

5-HT2 Serotonin Agonist that causes Hallucinations

A

Lysergic Acid Diethylamide

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2
Q

5-HT1A Serotonin Agonist for anti-anxiety

A

Buspirone

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3
Q

5-HT1D serotonin Agonist for excisting migraine

A

Sumatriptan

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4
Q

Effect of Sumatriptan on cerebral blood vessels

A

vasoconstriction

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5
Q

3 Serotonin direct Agonists

A

Lysergic Acid Diethylamide
Buspirone
Sumatriptan

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6
Q

Serotonin indirect agonist for Affective disorders, OCD, panic attacks

A

Fluoxetine

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7
Q

Fluoxetine’s Mechanism of action

A

SSRI– will increase serotonin in synapse

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8
Q

Side affects of Fluoxetine

A

nausea, sexual dysfunction

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9
Q

Serotonin indirect agonist for Narcolepsy and affective disorders

A

Phenelzine

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10
Q

Phenelzine mechanism of action

A

MAOI– increases serotonin in synapase

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11
Q

Side effect of Phenelzine

A

HTN crisis

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12
Q

2 serotonin indirect agonists

A

Fluoxetine–SSRI

Phenelzine–MAOI

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13
Q

Serotonin antagonist for Allergies, pruritis, utricaria, carcinoids

A

Cyproheptadine

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14
Q

Cyproheptadine acts on what receptor

A

a serotonin R antagonist on 5-HT2 & Histamine H1

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15
Q

Serotonin antagonist for Chemotherapy, post-op, and x-ray induced nausea and vomiting

A

Ondansetron

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16
Q

Ondansetron acts on which receptor

A

serotonin antagonist on 5-HT3

17
Q

Ondasetron acts on which system

A

CNS and GI

18
Q

Serotonin antagonist to tx Diarrhea predominant IBS in women

A

Alosetron

19
Q

Alosetron act on which receptor

A

serotonin antagonist on 5-HT3

20
Q

Adverse effects of Alosetron

A

Severe GI adverse effects (restrictive prescribing program)

Block 2 Drugs (10 decks)

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